US 2003/0198970 A1 · Genostics

Abstract

People vary enormously in their response to disease and the also in their response to therapeutic interventions aimed at ameliorating the disease process and progression. However, the provision of medical care and medical management is centered around observations and protocols developed in clinical trials on groups or cohorts of patients. This group data is used to derive a standardised method of treatment which is subsequently applied on an individual basis. There is considerable evidence that a significant factor underlying the individual variability in response to disease, therapy and prognosis lies in a person's genetic make-up. There have been numerous examples relating that polymorphisms within a given gene can alter the functionality of the protein encoded by that gene thus leading to a variable physiological response. In order to bring about the integration of genomics into medical practice and enable design and building of a technology platform which will enable the everyday practice of molecular medicine a way must be invented for the DNA sequence data to be aligned with the identification of genes central to the induction, development, progression and outcome of disease or physiological states of interest. According to the invention, the number of genes and their configurations (mutations and polymorphisms) needed to be identified in order to provide critical clinical information concerning individual prognosis is considerably less than the 100,000 thought to comprise the human genome. The identification of the identity of the core group of genes enables the invention of a design for genetic profiling technologies which comprises of the identification of the core group of genes and their sequence variants required to provide a broad base of clinical prognostic information—‘genostics’. The “GenosticTM” profiling of patients and persons will radically enhance the ability of clinicians, healthcare professionals and other parties to plan and manage healthcare provision and the targeting of appropriate healthcare resources to those deemed most in need. The use of our invention could also lead to a host of new applications for such profiling technologies, such as identification of persons with particular work or environment related risk, selection of applicants for employment, training or specific opportunities or for the enhancing the planning and organisation of health services, education services and social services.

A set of nucleotide probes for detecting relevant variants (mutations and polymorphisms), e.g. nucleotide substitutions (missense, nonsense, splicing and regulatory), small deletions, small insertions, small insertion deletions, gross insertions, gross deletions, duplications, complex rearrangements and repeat variations in a target group of genes;

said probes being complementary to DNA and RNA sequences of said group of genes;
characterised in that said group is a core group of genes consisting of substantially all of the following:
18 HUGO GENE PROTEIN CORE GENE LIST SYMBOL FUNCTION 11beta hydroxysteroid dehydrogenase 2 HSD11B2 E 17beta hydroxysteroid dehydrogenase 1 HSD17B1 E 17beta hydroxysteroid dehydrogenase 3 HSD17B3 E 17beta hydroxysteroid dehydrogenase 4 HSD17B4 E 17beta hydroxysteroid oxidoreductase E 18-hydroxysteroid oxidoreductase E 2,3-bisphosphoglycerate mutase BPGM E 2,4-dienoyl CoA reductase DECR E 3 beta hydroxysteroid dehydrogenase 2 HSD3B2 E 3-oxoacid CoA transferase OXCT E 4-hydroxyphenylpyruvate dioxygenase HPD E 5,10-methylenetetrahydrofolate reductase MTHFR E (NADPH) 5-adenosyl homocysteine hydrolase E 6-phosphofructo-2-kinase PFKFB1 E 6-pyruvoyltetrahydropterin synthase PTS E Acetoacetyl 1-CoA-thiolase ACAT1 E Acetoacetyl 2-CoA-thiolase ACAT2 E Acetyl CoA acyltransferase ACAA E Acetyl CoA carboxylase ACC E Acetyl CoA carboxylase alpha ACACA E Acetyl CoA synthase E Acetylcholinesterase ACHE E Acid phosphatase 2, lysosomal ACP2 E Aconitase E Acyl CoA dehydrogenase, long chain ACADL E Acyl CoA dehydrogenase, medium chain ACADM E Acyl CoA dehydrogenase, short chain ACADS E Acyl CoA dehydrogenase, very long chain ACADVL E Acyl CoA synthetase, long chain, 1 LACS1 E Acyl CoA synthetase, long chain, 2 LACS2 E Acyl CoA synthetase, long chain, 4 ACS4 E Acyl malonyl condensing enzyme E Acyl-CoA thioesterase E ADAM (A disintegrin and ADAM1 E metalloproteinase) 1 ADAM (A disintegrin and ADAM10 E metalloproteinase) 10 ADAM (A disintegrin and ADAM11 E metalloproteinase) 11 ADAM (A disintegrin and ADAM12 E metalloproteinase) 12 ADAM (A disintegrin and ADAM13 E metalloproteinase) 13 ADAM (A disintegrin and ADAM14 E metalloproteinase) 14 ADAM (A disintegrin and ADAM15 E metalloproteinase) 15 ADAM (A disintegrin and ADAM16 E metalloproteinase) 16 ADAM (A disintegrin and ADAM17 E metalloproteinase) 17 ADAM (A disintegrin and ADAM18 E metalloproteinase) 18 ADAM (A disintegrin and ADAM19 E metalloproteinase) 19 ADAM (A disintegrin and ADAM2 E metalloproteinase) 2 ADAM (A disintegrin and ADAM3A E metalloproteinase) 3A ADAM (A disintegrin and ADAM3B E metalloproteinase) 3B ADAM (A disintegrin and ADAM4 E metalloproteinase) 4 ADAM (A disintegrin and ADAM5 E metalloproteinase) 5 ADAM (A disintegrin and ADAM6 E metalloproteinase) 6 ADAM (A disintegrin and ADAM7 E metalloproteinase) 7 ADAM (A disintegrin and ADAM8 E metalloproteinase) 8 ADAM (A disintegrin and ADAM9 E metalloproteinase) 9 Adenosine deaminase ADA E Adenosine monophosphate deaminase AMPD E Adenylate cyclase 1 ADCY1 E Adenylate cyclase 2 ADCY2 E Adenylate cyclase 3 ADCY3 E Adenylate cyclase 4 ADCY4 E Adenylate cyclase 5 ADCY5 E Adenylate cyclase 6 ADCY6 E Adenylate cyclase 7 ADCY7 E Adenylate cyclase 8 ADCY8 E Adenylate cyclase 9 ADCY9 E Adenylate kinase AK1 E Adenylate transferase E Adenylosuccinate lyase ADSL E ADP-ribosyltransferase ADPRT E Adrenoleukodystrophy gene ALD E Alanine-glyoxylate aminotransferase AGXT E Alcohol dehydrogenase 1 ADH1 E Alcohol dehydrogenase 2 ADH2 E Alcohol dehydrogenase 3 ADH3 E Alcohol dehydrogenase 4 ADH4 E Alcohol dehydrogenase 5 ADH5 E Alcohol dehydrogenase 6 ADH6 E Alcohol dehydrogenase 7 ADH7 E Aldehyde dehydrogenase 1 ALDH1 E Aldehyde dehydrogenase 10 ALDH10 E Aldehyde dehydrogenase 2 ALDH2 E Aldehyde dehydrogenase 5 ALDH5 E Aldehyde dehydrogenase 6 ALDH6 E Aldehyde dehydrogenase 7 ALDH7 E Aldolase A ALDOA E Aldolase B ALDOB E Aldolase C ALDOC E Alkylglycerone phosphate synthase AGPS E alpha1-antichymotrypsin AACT E alphal-antitrypsin PI E alpha2-antiplasmin PLI E alpha-amino adipic semialdehyde synthase E alpha-amylase E alpha-dextrinase E alpha-Galactosidase A GLA E Alpha-galactosidase B, GALB NAGA E alpha-glucosidase, neutral C GANC E alpha-glucosidase, neutral AB GANAB E Peptidylglycine alpha-amidating PAM E monooxygenase alpha-ketoglutarate dehydrogenase E alpha-L-Iduronidase IDUA E Aminomethyltransferase AMT E Aminopeptidase P XPNPEP2 E Amylo-1,6-glucosidase AGL E Angiotensin converting enzyme ACE, DCP1 E Angiotensinogen AGT E Antithrombin III AT3 E Apurinic endonuclease APE E Arginase ARG1 E Arginosuccinate lyase ASL E Arginosuccinate synthetase ASS E Arylsulfatase A ARSA E Arylsulfatase B ARSB E Arylsulfatase C ARSC1 E Arylsulfatase D ARSD E Arylsulfatase E ARSE E Arylsulfatase F ARSF E Asparagine synthetase AS E Aspartate transcarbamoylase E Aspartoacylase ASPA E Aspartylglucosaminidase AGA E ATP cobalamin adenoxyltransferase E ATP sulphurylase atpsk2 E ATP/ADP translocase E beta-galactosidase GLB1 E beta-glucosidase, neutral E beta-Glucuronidase GUSB E beta-ketoacyl reductase E beta-N-acetylhexosaminidase, A E beta-N-acetylhexosaminidase, B E Bile acid coenzyme A:
amino acid BAAT E N-acyltransferase Bile salt-stimulated lipase CEL E Bilirubin UDP-glucuronosyltransferase E Biotinidase BTD E Bleomycin hydrolase BLMH E Branched chain aminotransferase 1, BCAT1 E cytosolic Branched chain aminotransferase 2, BCAT2 E mitochondrial Branched chain keto acid BCKDHA E dehydrogenase E1, alpha polypeptide Branched chain keto acid BCKDHB E dehydrogenase E1, beta polypeptide Brush border guanylyl cyclase E Butyrylcholinesterase BCHE E C1 inhibitor E C17-20 desmolase E C3 convertase E Calpain CAPN, CAPN3 E Carbamoylphosphate synthetase 1 CPS1 E Carbamoylphosphate synthetase 2 CPS2 E Carbonic anhydrase, alpha CA1 E Carbonic anhydrase, beta CA2 E Carbonic anhydrase 3 CA3 E Carbonic anhydrase 4 CA4 E Carboxylesterase 1 CES1 E Carboxypeptidase CPN E Carnitine acetyltransferase CRAT E Carnitine acylcarnitine translocase CACT E Carnitine palmitoyltransferase I CPT1A E Carnitine palmitoyltransferase II CPT2 E Catechol-O-methyltransferase COMT E Cathepsin B E Cathepsin D E Cathepsin E E Cathepsin G CTSG E Cathepsin H E Cathepsin K CTSK E Cathepsin L E Cathepsin S E Caveolin 3 CAV3 E Ceruloplasmin precursor CP E Chitotriosidase chit E Cholesterol ester hydroxylase E Choline acetyltransferase CHAT E Chymase CHY1 Chymotrypsinogen E Citrate synthase E CoA transferase E Coenzyme Q (CoQ)/ubiquinone E Collagenic-like tail subunit of asymmetric COLQ E acetylcholinesterase Complex I E Complex II E Complex III E Complex III E Complex V MTATP6 E Coproporphyrinogen oxidase CPO E Creatine kinase—B and m CKBE E Cu2+ transporting ATPase alpha ATP7A E polypetide Cu2+ transporting ATPase beta ATP7B E polypeptide Cyclic nucleotide phosphodiesterase 1B PDE1B E Cyclic nuclcotide phosphodiesterase 1B1 PDE1B1 E Cyclic nucleotide phosphodiesterase 2A3 PDE2A3 E Cyclic nucleotide phosphodiesterase 3A PDE3A E Cyclic nucleotide phosphodiesterase 3B PDE3B E Cyclic nucleotide phosphodiesterase 4A PDE4A E Cyclic nucleotide phosphodiesterase 4C PDE4C E Cyclic nucleotide phosphodiesterase 5A PDE5A E Cyclic nucleotide phosphodiesterase 6A PDE6A E Cyclic nucleotide phosphodiesterase 6B PDE6B E Cyclic nucleotide phosphodiesterase 7 PDE7 E Cyclic nucleotide phosphodiesterase 8 PDE8 E Cyclic nucleotide phosphodiesterase 9A PDE9A E Cyclooxygenase 1 COX1 E Cyclooxygenase 2 COX2 E CYP11A1 CYP11A1 E CYP11B1 CYP11B1 E CYP11B2 CYP11B2 E CYP17 CYP17 E CYP19 CYP19 E CYP1A1 CYP1A1 E CYP1A2 CYP1A2 E CYP1B1 CYP1B1 E CYP21 CYP21 E CYP24 CYP24 E CYP27 CYP27 E CYP27B1 PDDR E CYP2A1 CYP2A1 E CYP2A13 CYP2A13 E CYP2A3 CYP2A3 E CYP2A6V2 CYP2A6V2 E CYP2A7 CYP2A7 E CYP2B6 CYP2B6 E CYP2C18 CYP2C18 E CYP2C19 CYP2C19 E CYP2C8 CYP2C8 E CYP2C9 CYP2C9 E CYP2D6 CYP2D6 E CYP2E1 CYP2E1 E CYP2F1 CYP2F1 E CYP2J2 CYP2J2 E CYP3A3 CYP3A3 E CYP3A4 CYP3A4 E CYP3A5 CYP3A5 E CYP3A7 CYP3A7 E CYP4A11 CYP4A11 E CYP4B1 CYP4B1 E CYP4F2 CYP4F2 E CYP4F3 CYP4F3 E CYP51 CYP51 E CYP5A1 CYP5A1 E CYP7A CYP7A E CYP8 CYP8 E Cystathionase CTH E Cystathione beta synthase CBS E Cytidine deaminase CDA E Cytidine-5-prime-triphosphate synthetase CTPS E Cytochrome a E Cytochrome b-245 alpha CYBA E Cytochrome b-245 beta CYBB E Cytochrome b-5 CYB5 E Cytochrome c E Cytochrome c oxidase, MTCO E D-beta-hydroxybutyrate dehydrogenase E Dehydratase E Delta 4-5 alpha-reductase E Delta 4-5 oxosteroid isomerase E Delta aminolevulinate dehydratase ALAD E Delta aminolevulinate synthase 1 ALAS1 E Delta aminolevulinate synthase 2 ALAS2 E Delta(4)-3-oxosteroid 5-beta reductase E Delta-7-dehydrocholesterol reductase DHCR7 E Deoxycorticosterone (DOC) receptor E Deoxycytidine kinase DCK E Deoxyuridine triphosphatase;
dUTPase E DHEA sulfotransferase STD E Dihydrodiol dehydrogenase 1 DDH1 E Dihydrofolate reductase DHFR E Dihydrolipoyl dehydrogenase E Dihydrolipoyl dehydrogenase 2 PDHA E Dihydrolipoyl succinyltransferase DLST E Dihydrolipoyl transacetylase PDHA E Dihydroorotase E Dihydropyramidinase DPYS E Dihydroxyacetonephosphate DHAPAT E acyltransferase Dihyropyrimidine dehydrogenase DPYD E DM-Kinase DMPK E DNA directed polymerase, alpha POLA E DNA glycosylases E DNA helicases E DNA Ligase 1 LIG1 E DNA methyltransferase DNMT E Methylguanine-DNA methyltransferase MGMT E DNA polymerase 1 E DNA polymerase 2 E DNA polymerase 3 E DNA primase E DNA-dependent RNA polymerase E DOPA decarboxylase DDC E Dopamine beta hydroxylase DBH E Dysferlin DYS, DYSF E Dystrophia myotonica DM, DMPK E Dystrophia myotonica, atypical DM2 E Elastase 1 ELAS1 E Elastase 2 ELAS2 E Electron-transferring flavoprotein ETFDH E dehydrogenase Enolase ENO1 E Enoyl CoA hydratase E Enoyl CoA isomerase E Enoyl CoA reductase E Enterokinase PRSS7, ENTK E Eosinophil peroxidase EPX E Epilepsy, benign neonatal 4 gene ICCA E Epilepsy, female restricted EFMR E Epilepsy, progressive myoclonic 2 gene EPM2A E Epoxide hydrolase 1, microsomal EPHX1 E Excision repair complementation ERCC1 E group 1 protein Excision repair complementation ERCC2 E group 2 protein Excision repair complementation ERCC3 E group 2 protein Excision repair complementation ERCC4 E group 4 protein Excision repair complementation ERCC6 E group 6 protein FADH dehydrogenase E Ferrochelatase FECH E Flavin-containing monooxygenase 1 FMO1 E Flavin-containing monooxygenase 2 FMO2 E Flavin-containing monooxygenase 3 FMO3 E Flavin-containing monooxygenase 4 FMO4 E Formiminotransferase E Fructose-1,6-diphosphatase FBP1 E Fucosidase alpha-L-1 FUCA1 E Fucosidase alpha-L-2 E Fumarase FH E Fumarylacetoacetase FAH E GABA transaminase ABAT E Gadd45 (growth arrest & E DNA-damage-inducible protein) Galactocerebrosidase GALC E Galactokinase GALK1 E Galactose 1-phosphate uridyl-transferase GALT E Gastric Intrinsic factor, GIF GIF E Glucokinase GCK E Glucosaminyl (N-acetyl) transferase 2, GCNT2 E I-branching enzyme Glucose-6-phosphatase G6PC E Glucose-6-phosphatase translocase G6PT1 E Glucose-6-phosphate dehydrogenase G6PD E Glucosidase, acid alpha GAA E Glucosidase, acid beta GBA E Glutamate decarboxylase, GAD GAD1 E Glutamate dehydrogenase GLUD1 E Glutamate-cysteine ligase GLCLC E Glutamine phosphoribosylpyrophosphate E amidotransferase/PRPP amidotransferase Glutamine synthase E Glutaryl-CoA dehydrogenase GCDH E Glutathione peroxidase, GPX1 GPX1 E Glutathione peroxidase, GPX2 GPX2 E Glutathione reductase, GSR GSR E Glutathione S-transferase mu 1, GSTM1 GSTM1 E Glutathione S-transferase mu 4, GSTM4 E Glutathione S-transferase theta 1, GSTT1 GSTT1 E Glutathione S-transferase theta 2, GSTT2 E Glutathione S-transferase, GSTP1 GSTP1 E Glutathione S-transferase, GSTZ1 GSTZ1 E Glutathione synthetase GSS E Glyceraldehyde-3-phosphate GAPDH E dehydrogenase, GADPH Glycerol kinase GK E Glycerophosphate dehydrogenase 2 GPD2 E Glycinamide ribonucleotide (GAR) GART E transformylase Glycine dehydrogenase GLDC E Glycogen branching enzyme GBE1 E Glycogen phosphorylase PYGL E Glycogen synthase 1 (muscle) GLYS1 E Glycogen synthase 2 (liver) GYS2 E Glycosyltransferases, ABO blood group ABO E GM2 ganglioside activator protein, GM2A GM2A E Guanidinoacetate N-methyltransferase GAMT E Guanylate cyclase 2D, membrane GUCY2D E (retina-specific) Guanylate cyclase activator 1A (retina) GUCA1A E Guanylate kinase E Guanylyl cyclase E Hacme regulated inhibitor kinase E Heparan sulfamidase E Hepatic lipase LIPC E Hepatic nuclear factor-3-beta HNF3B E Hepatic nuclear factor-4-alpha HNF4A E Hexokinase 1 HK1 E Hexokinase 2 HK2 E Hexosaminidase A HEXA, TSD E Hexosaminidase B HEXB E Histidase E HMG-CoA lyase HMGCL E HMG-CoA reductase HMGCR E HMG-CoA synthase HMGCS2 E Holocarboxylase synthetase HLCS E Homogentisate 1,2 dioxygenase HGD E Hormone-sensitive lipase HSL E HSSB, replication protein E Hydroxyacyl glutathione hydrolase HAGH E Hypoxanthine-guanine HPRT E phosphoribosyltransferase, HGPRT Hypoxia inducible factor 1 HIF1A E Hypoxia inducible factor 2 E Ibonucleoside diphosphate reductase E Iduronate 2 sulphatase IDS E Inosine monophosphate dehydrogenase, E IMPDH Inosine triphosphatase ITPA E Inter-alpha-trypsin inhibitor, IAT1 E Iodothyronine-5′-deiodinase, type 1 and 2 E IP3 kinase E Isocitrate dehydrogenase E Isovaleric acid CoA dehydrogenase IVD E Ketohexokinase KHK E ketolase E Kynurenine hydroxylase E Kynureninease E Lactase E Lactate dehydrogenase, A LDHA E Lactate dehydrogenase, B LDHB E Lecithin-cholesterol acyltransferase LCAT E Leukotriene A4 synthase LTA4S E Leukotriene B4 synthase LTB4S E Leukotriene C4 synthase LTC4S E Lipoamide dehydrogenase OGDH E Lipoxygenase E Lowe oculocerbrorenal syndrome gene OCRL E Lysosomal acid lipase LIPA E Lysyl hydroxylase PLOD E Lysyl oxidase LOX E Malate dehydrogenase, mitochondrial MDH2 E Malonyl CoA decarboxylase E Malonyl CoA transferase E Maltase-glucoamylase E Mannosidase, alpha B lysosomal MANB E Mannosidase, beta A lysosomal MANBA E Matrix metalloproteinase 1 MMP1 E Matrix metalloproteinase 10 MMP10 E Matrix metalloproteinase 11 MMP11 E Matrix metalloproteinase 12 MM12 E Matrix metalloproteinase 13 MMP13 E Matrix metalloproteinase 14 MMP14 E Matrix mctalloproteinase 15 MMP15 E Matrix metalloproteinase 16 MMP16 E Matrix metalloproteinase 17 MMP17 E Matrix metalloproteinase 18 MMP18 E Matrix metalloproteinase 19 MMP19 E Matrix metalloproteinase 2 MMP2 E Matrix metalloproteinase 3 MMP3, E STMY1 Matrix metalloproteinase 4 MMP4 E Matrix metalloproteinase 5 MMP5 E Matrix metalloproteinase 6 MMP6 E Matrix metalloproteinase 7 MMP7 E Matrix metalloproteinase 8 MMP8 E Matrix metalloproteinase 9 MMP9 E MEK kinase, MEKK E Methionine adenosyltransferase MAT1A, E MAT2A Methionine synthasc MTR E Methionine synthase reductase MTRR E Methylmalonyl-CoA mutase MUT E Mevalonate kinase MVK E Mitochondrial trifunctional protein, alpha HADHA E Mitochondrial trifunctional protein, HADHB E beta subunit Molybdenum cofactor synthesis 1 MOCS1 E Molybdenum cofactor synthesis 2 MOCS2 E Monoamine oxidase A MAOA E Monoamine oxidase B MAOB E Mucolipidoses GNPTA E Muscle phosphorylase PYGM E N-acetylgalactosamine-6-sulfate sulfatase GALNS E N-acetylglucosamine-6-sulfatase GNS E N-acetylglucosaminidase, alpha NAGLU E N-acetyltransferase 1 NAT1 E N-acetyltransferase 2 NAT2 E NADH dehydrogenase E NADH dehydrogenase (ubiquinone) Fe-S NDUFS1 E NADH dehydrogenase (ubiquinone) Fe-S NDUFS4 E NADH dehydrogenase (ubiquinone) NDUFV1 E NADH-cytochrome b5 reductase DIA1 E NADPH-dependent cytochrome POR E P450 reductase Neuroendocrine convertase 1 NEC1, PCSK1 E Neutral endopeptidase E Nitric oxide synthase 1, NOS1 NOS1 E Nitric oxide synthase 2, NOS2 NOS2 E Nitric oxide synthase 3, NOS3 NOS3 E Nucleoside diphosphate kinase-A NDPKA E Ornithine delta-aminotransferase OAT E Ornithine transcarbamoylase OTC, NME1 E Pancreatic amylase E Pancreatic lipase PNLIP E Pancreatic lipase related protein 1 PLRP1 E Pancreatic lipase related protein 2 PLRP2 E Paraoxonase PON1 PON1 E Paraoxonase PON2 PON2 E Paraoxonase PON3 E PCNA (proliferating cell nuclear antigen) E Pepsinogen E Peroxidase, salivary SAPX E Phenylalanine hydroxylase PAH E Phenylalanine monooxygenase E Phenylethanolamine N-methyltransferase, PNMT E Phosphoenolpyruvate carboxykinase PCK1 E Phosphofructokinase, liver PFKL E Phosphofructokinase, muscle PFKM E Phosphoglucomutase E Phosphoglucose isomerase GPI E Phosphoglycerate kinase 1 PGK1 E Phosphoglycerate mutase 2 PGAM2 E Phosphoribosyl pyrophosphate synthetase PRPS1 E Phosphorylase kinase deficiency, liver PHK E Phosphorylase kinase, alpha 1 (muscle) PHKA1 E Phosphorylase kinase, alpha 2 PHKA2 E Phosphorylase kinase, beta PHKB E Phosphorylase kinase, delta E Phosphorylase kinase, gamma 2 PHKG2 E Pineolytic beta-receptors E Plasminogen PLG E Plasminogen activator inhibitor 1 PAI1 E Plasminogen activator inhibitor 2 PAI2 E Plasminogen activator receptor, Urokinase UPAR;
S PLAUR Plasminogen activator, Tissue PLAT;
TPA E Plasminogen activator, Urokinase UPA;
PLAU E Poly (ADP-ribose) synthetase PARS E Porphobilinogen deaminase HMBS E Procollagen N-protease E Procollagen peptidase E Proline dehydrogenase PRODH E Prolyl-4-hydroxylase E Propionyl-CoA carboxylase, alpha PCCA E Propionyl-CoA carboxylase, beta PCCB E Prostasin, PRSS8 PRSS8 E Protease nexin 2 PN2 E Protective protein for beta-galactosidase PPGB E Protein kinase A E Protein kinase B PRKB Protein kinase C, alpha PRKCA E Protein kinase C, gamma PRKCG E Protein kinase DNA-activated PRKDC E Protein kinase G E Protein phosphatase 1, regulatory PPP1R3 E (inhibitor) Protein phosphatase 2, regulatory PPP2R1B E subunit A, isoform Protoporphyrinogen oxidase PPOX E Pterin-4-alpha-carbinolamiine PCBD Purine nucleoside phosphorylase NP E Pyrroline-5-carboxylase synthetase PYCS E Pyruvate carboxylase PC E Pyruvate decarboxylase PDHA E Pyruvate kinase PKLR E Quinoid dihydropteridine reductase QDPR E Renin REN E Replication factor A E Replication factor C RFC2 E Rhodopsin kinase RHOK E Ribonucleotide reductase, RRM E Ribosephosphate pyrophosphokinase E Ribosomal protein L13A RPL13A G Ribosomal protein L17 RPL17 G Ribosomal protein S19 RPS 19 E Ribosomal protein S4, X-linked RPS4X E Ribosomal protein S6 kinase RPS6KA3 E Ribosomal protein S9 RPS9 G S-adenosylmethionine decarboxylase, E AMD Serine hydroxymethyltransferase SHMT E Serotonin N-acetyltransferase SNAT E Sorbitol dehydrogenase SORD E Sphingomyelinase SMPD1 E Steroid 5 alpha reductase 1 SRD5A1 E Steroid 5 alpha reductase 2 SRD5A2 E Steroid sulphatase STS E Succinate dehydrogenase 1 SDH1 E Succinate dehydrogenase 2 SDH2 E Succinate thiokinase E Succinic semi-aldehyde dehydrogenase ssadh E Succinyl CoA synthase E Sucrase E Sulfite oxidase SUMOX E Superoxide dismutase 1 SOD1 E Superoxide dismutase 3 SOD3 E TEK, tyrosine kinase, endothelial TEK E Telomerase protein component E Terninal deoxynucleotidyltransferase, E TDT Thiolase, perioxisomal E Thiopurine S-methyltransferase TPMT E Thymidylate synthase TYMS E Tissue inhibitor of metalloproteinase 1, TIMP1 E TIMP1 Tissue inhibitor of metalloproteinase 2, TIMP2 E TIMP2 Tissue inhibitor of metalloproteinase 3, TIMP3 E TIMP3 Tissue inhibitor of metalloproteinase 4, TIMP4 E TIMP4 Tissue non-specific alkaline phosphatase E Topoisomerase I E Topoisomerase II E Transacylase E Transketolase TKT E Transketolase-like 1 TKTL1 E Triosephosphate isomerase TPI1 E Trypsin inhibitor E Trypsinogen 1 TRY1 E Trypsinogen 2 TRY2 E Tryptophan hydroxylase TPH E Tyrosinase TYR E Tyrosinase-related protein 1 TYRP1 E Tyrosine amninotransferase TAT E Tyrosine hydroxylase TH E Ubiquitin activating enzyme, E1 E Ubiquitin protein ligase E3A UBE3A E UDP-glucose pyrophosphorylase E UDP-glucuronosyltransferase 1 ugt1d, UGT1 E UDP-glucuronosyltransferase 2 UGT2 E Urate oxidase UOX E Ureidopropionase E Uridinediphosphate(UDP)-galactose-4- GALE E Uroporphyrinogen decarboxylase UROD E Uroporphyrinogen III synthase UROS E Xanthine dehydrogenase XDH E Xerodenna pigmentosum, XPA E complementation A Xeroderma pigmentosum, XPB E complementation B Xeroderma pigmentosum, XPC E complementation C Xeroderma pigmentosum, E complementation D Xeroderma pigmentosum, E complementation E Xeroderma pigmentosum, XPF E complementation F Xeroderma pigmentosum, ERCC5 E complementation G Xylitol dehydrogenase E Acidic amino acid transporter T Adaptin, beta 3A ADTB3A T Adenine phosphoribosyltransferase APRT T Alanine aminotransferase T Albumin, ALB ALB T Aldose reductase T Alkaline phosphatase, liver/bone/kidney ALPL T Alpha 1 acid glycoprotein AAG;
AGP T Androgen binding protein ABP T Angiotensin receptor 1 AGTR1 T Angiotensin receptor 2 AGTR2 T Antidiuretic homione receptor ADHR T Apolipoprotein (a) LPA T Apolipoprotein A 4 APOA4 T Apolipoprotein A I APOA1 T Apolipoprotein A II APOA2 T Apolipoprotein B APOB T Apolipoprotein Cl APOC1 T Apolipoprotein C2 APOC2 T Apolipoprotein C3 APOC3 T Apolipoprotein D APOD T Apolipoprotein E APOE T Apolipoprotein H APOH T Aquaporin 1 AQP1 T Aquaporin 2 AQP2 T Aryl hydrocarbon receptor AHR T Aryl hydrocarbon receptor nuclear ARNT T translocator Aspartate transaminase T Bestrophin VMD2 T Bile salt export pump BSEP, PFIC2 T Biliverdin reductase T Ca(2+) transporting ATPase, fast twitch ATP2A1 T Ca(2+) transporting ATPase, slow twitch ATP2A2 T Calcium sensing receptor CASR T Calmodulin dependant kinase T Canalicular multispecific organic anion CMOAT T Carnitine transporter protein CDSP, SCD T Chediak-Higashi syndrome 1 gene CHS1 T Cholesterol ester transfer protein CETP T Clathrin T Cortico-steroid binding protein T Corticotrophin-releasing hormone CRH T Corticotrophin-releasing hormone receptor CRHR1 T Cubilin CUBN T Cystatin B CSTB T Cystatin C CST3 T Cysteine-rich intestinal protein T Cystinosin CTNS T Diastrophic dysplasia sulfate transporter DTD T Duffy blood group FY T Electron-transfering-flavoprotein alpha ETFA T Electron-transfering-flavoprotein beta ETFB T Emerin EMD T Enteric lipase T Faciogenital dysplasia FGD1, FGDY T Fanconi anemia, complementation FANCA T group A Fanconi anemia, complementation FANCC T group C Fanconi anemia, complemnentation FANCD T group D Fatty acid binding proteins FABP1 T Fatty acid binding proteins FABP2 FABP2 T Fatty acid binding proteins FABP3 T Fatty acid binding proteins FABP4 T Fatty acid binding proteins FABP5 T Fatty acid binding proteins FABP6 T Ferritin, H subunit T Ferritin, L subunit FTL T Fucosyltransferase 2 FUT2 T Fucosyltransferase 3 FUT3 T Fucosyltransferase 6 FUT6 T Furin T Gamma-glutamnyl carboxylase GGCX T Gamma-glutamyltransferase 1 GGT1 T Gamma-glutamyltransferase 2 GGT2 T Gap junction protein alpha 1 GJA1 T Gap junction protein alpha 3 GJA3 T Gap junction protein alpha 8 GJA8 T Gap junction protein beta 1 GJB1 T Gap junction protein beta 2 GJB2 T Gap junction protein beta 3 GJB3 T Gastric inhibitory polypeptide GIP GIP T Gastric inhibitory polypeptide receptor, GIPR T GIPR Gastric lipase, LIPF T Gastrin releasing peptide GRP T Gastrin releasing peptide receptor GRPR T Glucagon synthase T Glutamine transporter T Glutathione GSH T Guanylin GUCA2 T Haem oxygenase T Haemoglobin alpha 1 HBA1 T Haemoglobin alpha 2 HBA2 T Haemoglobin beta HBB T Haemoglobin delta HBD T Haemoglobin epsilon T Haemoglobin gamma A HBG1 T Haemoglobin gamma B HBG2 T Haemoglobin gamma G HBGG T Hcmochromatosis HFE T Hermansky-pudlak syndrome gene HPS T Histidine-rich glycoprotein HRG T Huntingtin HD T Hyaluronidase T Intestinal alkaline phosphatase IAP T Kell blood group precursor XK, KEL T Lactotransferrin LTF T Lipoprotein receptor, Low Density LDLR T Lipoprotein, High Density HDLDT1 T Lipoprotein, Intermediate Density T Lipoprotein, Low Density 1 T Lipoprotein, Low Density 2 T Lipoprotein, Very Low Density VLDLR T Long QT-type 2 potassium channels LQT2, KCNH2 T Low density lipoprotein receptor-related LRP T protein precursor Mannosyl (alpha-1,6-)-glycoprotein MGAT2 T beta-1,2-acetylglucosaminyltransferase Marenostrin MEFV T Melanocortin 1 receptor MC1R T Melanocortin 2 receptor MC2R T Melanocortin 4 receptor MC4R T Metallothionein T Microsomal triglyceride transfer protein MTP T Mucin 18 MUC18 T Mucin, MUC2 T Mucin, MUC5AC T Mucin, MUC6 T Mulibrey nanism MUL T Myocilin MYOC T Myoglobin T Myopia 1 MYP1 T Myopia 2 MYP2 T Na+/H+ exchanger 1 NHE1 T Na+/H+ exchanger 2 NHE2 T Na+/H+ exchanger 3 NHE3 T Na+/H+ exchanger 4 NHE4 T Na+/H+ exchanger 5 NHE5 T Na + coupled glucose/galactose T transporter Nephrolithiasis 2 NPHL2 T Nephronophthisis 1 NPHP1 T Ncphronophthisis 2 NPHP2 T Nephrosis 1 NPHS1 T Neuraminidase sialidase NEU T Niemann-Pick disease protein NPC1 T Nucleophosmin NPM1 T Palmitoyl-protein thioesterase PPT T Pancreatic colipase T Pendrin, PDS PDS T Pepsin T Peptidascs A T Peptidascs B T Peptidases C T Peptidases D PEPD T Peptidases E T Peptidases S T Peroxisomal membrane protein 3 PXMP3 T Peroxisome biogenesis factor 1 PEX1 T Peroxisome biogenesis factor 6 PEX6 T Peroxisome biogenesis factor 7 PEX7 T Peroxisome biogencsis factor 19 PEX19 T Peroxisome proliferative activated PPARA T receptor, Peroxisome proliferative activated PPARG T receptor, Peroxisome receptor 1 PXR1 T P-glycoprotein 1 PGY1 T P-glycoprotein 3 PGY3 T Phosphomannomutase-2 PMM2 T Phosphomannose isomerase-1, PMI1 MPI T Plakophilin 1 PKP1 T Platelet glutaminase GLS T Platelet monoamine oxidase T Plectin 1 PLEC1 T Polycystic kidney and hepatic disease 1 PKHD1 T Polycystin 1 PKD1 T Polycystin 2 PKD2 T Polymorphonuclear elastase T Preproglucagon T Preproinsulin T Presenilin 1 PSEN1 T Presenilin 2 PSEN2 T Prostaglandin I2 receptor T Protease inhibitor 1 T Renal glutaminase T Retinaldehyde binding protein 1 RLBP1 T Retinol binding protein 1 T Retinol binding protein 2 T Retinol binding protein 4 RBP4 T Rhesus blood group, CcEe antigens RHCE T Rhesus blood group, D antigen RHD T Rhesus blood group-associated RHAG T glycoprotein Salivary amylase, AMY1 T Secretin SCT T Secretin receptor, SCTR SCTR T Serum amyloid A SAA T Serum amyloid P SAP T Sex honnone binding globulin, SHBG T Solute carrier family 1 (amino acid SLC1A6 T transporter), member 6 Solute carrier family 1 (glial high affinity SLC1A3 T transporter), member 3 Solute carrier family 1 (glutamate SLC1A1 T transporter), member 1 Solute carrier family 1 (glutamate SLC1A2 T transporter), member 2 Solute carrier family 1 (neutral amino acid SLC1A4 T transporter), member 4 Solute carrier family 10 (sodium/bile acid SLC10A1 T cotransporter family), member 1 Solute carrier family 10 (sodium/bile acid SLC10A2 T cotransporter family), membcr 2 Solute carrier family 12, member 1 SLC12A1 T Solute carrier family 12, member 2 SLC12A2 T Solute carrier family 12, member 3 SLC12A3 T Solute carrier family 14, member 2 SLC14A2 T Solute carrier family 15 (H+/peptide SLC15A1 T intestinal), member 1 Solute carrier family 15 (H+/peptide SLC15A2 T kidney), member 2 Solute carrier family 16 (monocarboxylate SLC16A1 T transporter), member 1 Solute carrier family 16 (monocarboxylate SLC16A7 T transporter), member 7 Solute carrier family 17, member 1 SLC17A1 T Solute carrier family 17, member 2 SLC17A2 T Solute carrier family 18, member 3 SLC18A3 T Solute carrier family 19 (folate SLC19A1 T transporter), member 1 Solute carrier family 2 (facilitated glucose SLC2A1 T transporter), member 1 Solute carrier family 2 (facilitated glucose SLC2A2 T transportEr), member 2 Solute carrier family 2 (facilitated glucose SLC2A3 T transporter), member 3 Solute carrier family 2 (facilitated glucose SLC2A4 T transporter), member 4 Solute carrier family 2 (facilitated glucose SLC2A5 T transporter), member 5 Solute carrier family 20, member 1 SLC20A1 T Solute carrier family 20, member 2 SLC20A2 T Solute carrier family 20, member 3 SLC20A3 T Solute carrier family 21, member 2 SLC21A2 T Solute carrier family 21, member 3 SLC21A3 T Solute carrier family 22, member 1 SLC22A1 T Solute carrier family 22, member 2 SLC22A2 T Solute carrier family 22, member 5 SLC22A5 T Solute carrier family 25, member 12 SLC25A12 T Solute carrier family 3 (facilitated glucose SLC3A1 T transporter), member 1 Solute carrier family 4 (anion SLC4A1 T exchanger), 1 Solute carrier family 4 (anion SLC4A2 T exchanger), 2 Solute carrier family 4 (anion SLC4A3 T exchanger), 3 Solute carrier family 5 (sodium/glucose SLC5A1 T transporter), member 1 Solute carrier family 5 (sodium/glucose SLC5A2 T transporter), member 2 Solute carrier family 5 (sodium/glucose SLC5A5 T transporter), member 5 Solute carrier family 5, member 3 SLC5A3 T Solute carrier family 6 (GAMMA- SLC6A1 T AMINOBUTYRIC ACID transporter), member Solute carrier family 6 (neurotransmitter SLC6A3 T transporter, dopamine), member 3 Solute carrier family 6 (neurotransmitter SLC6A2 T transporter, noradrenaline), member 2 Solute carrier family 6 (neurotransmitter SLC6A4 T transporter, serotonin), member 4 Solute carrier family 6, member 10 SLC6A10 T Solute carrier family 6, member 6 SLC6A6 T Solute carrier family 6, member 8 SLC6A8 T Solute carrier family 7(amino acid SLC7A1 T transporter), member 1 Solute carrier family 7(amino acid SLC7A2 T transporter), member 2 Solute carrier family 7(amino acid SLC7A7 T transporter), member 7 Solute carrier family 8 (sodium/calcium SLC8A1 T member 1 Sorcin SRI T Steroidogenic acute regulatory protein STAR T Sterol carrier protein 2 SCP2 T Stratum corneum chymotryptic enzyme T Sucrase-isomaltase S1 T Surfactant pulmonary-associated SFTPA1 T protein A1 Surfactant pulmonary-associated SFTPA2 T protein A2 Surfactant pulmonary-associated SFTPB T protein B Surfactant pulmonary-associated SFTPC T protein C Surfactant pulmonary-associated SFTPD T protein D Survival of motor neuron 1, telomeric SMN1 T Tetranectin TNA T Thyroxin-binding globulin TBG T Tocopherol (alpha) transfer protein TTPA T Transcobalamin 1, TCN1 T Transcobalamin 2, TCN2 TCN2 T Transthyretin TTR T Trehalase T Trypsinogen activation peptide T Uncoupling protein 1 T Uncoupling protein 3 UCP3 T Uteroglobin UGB T Vitelliforn macular dystrophy, VMD1 T atypical gene Vitronectin receptor, alpha VNRA T Von Willebrand factor VWF T Achromatopsia 2 ACHM2 S Actin, alpha, skeletal ACTA1 S Actin, alpha, smooth, aortic ACTA2 S Actin, alpha, cardiac ACTC S Actin, beta ACTB S Actin, gamma 2 ACTG2 S Adducin, alpha ADD1 S Adducin, beta ADD2 S Amelogenin AMELX S Ankyrin 1 ANK1 S Ankyrin 2 ANK2 S Ankyrin 3 ANK3 S Apaf-1 S Arrestin SAG S Blue cone pigment BCP S Chloride channel 1, skeletal muscle CLCN1 S Chloride channel 5 CLCN5 S Chloride channel KB CLCNKB S Choroideremia gene CHM S Cofilin S Collagen I alpha 1 COL1A1 S Collagen I alpha 2 COL1A2 S Collagen II alpha 1 COL2A1 S Collagen III alpha 1 COL3A1 S Collagen IV alpha 1 COL4A1 S Collagen IV alpha 2 COL4A2 S Collagen IV alpha 3 COL4A3 S Collagen IV alpha 4 COL4A4 S Collagen IV alpha 5 COL4A5 S Collagen IV alpha 6 COL4A6 S Collagen IX alpha 2 COL9A2, S EDM2 Collagen IX alpha 3 COL9A3 S Collagen receptor COLR S Collagen V alpha 1 COL5A1 S Collagen V alpha 2 COL5A2 S Collagen VI alpha 1 COL6A1 S Collagen VI alpha 2 COL6A2 S Collagen VI alpha 3 COL6A3 S Collagen VII alpha 1 COL7A1 S Collagen X alpha 1 COL10A1 S Collagen X alpha 1 COL11A1 S Collagen XI alpha 2 COL11A2 S Collagen XVII alpha 1 COL17A1 S Cryptochrome 1 CRY1 S Cryptochrome 2 CRY2 S Crystallin, alpha A CRYAA S Crystallin, alpha B CRYAB S Crystallin, beta B2 CRYBB2 S Crystallin, gamma A CRYGA S Desmin DES S DNA damage binding protein, DDB1 DDB1 S DNA damage binding protein, DDB2 DDB2 S DNA-damage-inducible transcript 3 DDIT3 S Doublecortin, DCX DCX S Dyskerin DKC1 S Dystonia 1 DYT1 S Dystonia 3 DYT3 S Dystonia 6 DYT6 S Dystonia 7 DYT7 S Dystonia 9 CSE S Dystrophin DMD S Dystrophin-associated glycoprotein 35kD, SGCD S Dystrophin-associated glycoprotein 35kD, SGCG S Dystrophin-associated glycoprotein 43kD SGCB S Dystrophin-associated glycoprotein 50kD SGCA S Ectodermal Dysplasia 1 gene ED1 S Elastin ELN S Endocardial fibroelastosis 2 gene EFE2 S Endoglin ENG S Erythrocyte membrane protein band 4.1 EPB41 S Erythrocyte membrane protein band 4.2 EPB42 S Erythrocyte membrane protein band 7.2 EPB72 S Exostosin 1 EXT1 S Exostosin 2 EXT2 S Exostosin 3 EXT3 S Eye colour gene 3 (brown) EYCL3 S Fibrinogen alpha FGA S Fibrinogen beta FGB S Fibrinogen gamma FGG S Glycophorin A GYPA S Glycophorin B GYPB S Glycophorin C GYPC S Green cone pigment GCP S Keratin 1 KRT1 S Keratin 10 KRT10 S Keratin 11 KRT11 S Keratin 12 KRT12 S Keratin 13 KRT13 S Keratin 14 KRT14 S Keratin 15 KRT15 S Keratin 16 KRT16 S Keratin 17 KRT17, S PCHC1 Keratin 18 KRT18 S Keratin 2 KRT2 S Keratin 3 KRT3 S Keratin 4 KRT4 S Keratin 5 KRT5 S Keratin 6 KRT6 S Keratin 7 KRT7 S Keratin 8 KRT8 S Keratin 9 KRT9 S Keratin, hair acidic 1 KRTHA1 S Keratin, hair basic 2 KRTHB1 S Keratin, hair basic 6 KRTHB6 S Loricrin LOR S Microtuble associated protein MAP S Moesin, MSN S Myomesin 1 MYOM1 S Myomesin 2 MYOM2 S Myelin basic protein S Myelin protein peripheral 22 PMP22 S Myelin protein zero MPZ S Myosin 15 MYO15 S Myosin 5A MYO5A S Myosin 6 MYO6 S Myosin 7A MYO7A S Myosin, cardiac MYH7 S Myosin, light chain 2 MYL2 S Myosin, light chain 3 MYL3 S Myosin-binding protein C, cardiac MYBPC3 S Myotubularin MTM1 S Nebulin NEB S Neurofilament protein, heavy NFH S Neurofilament protein, NF125 NF150 S Neurofilament protein, NF200 NF200 S Neurofilament protein, NF68 NF68 S Ocular albinism I OA1 S Oculocutaneous albinism II OCA2 S Ostcocalcin S Peripherin, PRPH S Peroxisomal membrane protein 1 PXMP1 S Persyn S Proline-rich protein BstNI subfamily 1 PRB1 S Proline-rich protein BstNI subfamily 3 PRB3 S Proline-rich protein BstNI subfamily 4 PRB4 S Radixin/ RDX S Red cone pigment RCP S Retinal pigment epithelium specific RPE65 S protein Retinitis pigmentosa gene 1 RP1 S Retinitis pigmentosa gene 2 RP2 S Retinitis pigmentosa gene 3 RP3 S Retinitis pigmentosa gene 6 RP6 S Retinitis pigmentosa gene 7 RP7, RDS S Rhodopsin RPHO S Rod outer segment membrane protein 1 ROM1 S Semaphorin A4 SEMA4 S Semaphorin A5 SEMA5 S Semaphorin D S Semaphorin E SEMAE S Semaphorin F SEMA3/F S Semaphorin W SEMAW S Small nuclear ribonucleoprotein SNRPN S polypeptide N Spectrin alpha SPTA1 S Spectrin beta SPTB S Talin, TLN S Tau protein MAPT S Tenascin (cytotactin) S Tenascin XA TNXA S Titin TTN S Tropomyosin 1 alpha TPM1 S Tropomyosin 3 (non-muscle) TPM3 S Troponin C S Troponin I TNNI3 S Troponin T2, cardiac TNNT2 S Tubulin S Undulin 1 COL14A1 S Usher syndrome 2A USH2A S Villin S Vinculin S Wolfram syndrome 1 gene WFS1 S Zinc finger protein 198 ZIC198 S Zinc finger protein 2 ZIC2 S Zinc finger protein 3 ZIC3 S Zinc finger protein HRX ALL1 I Alpha 2 macroglobulin A2M I Annexin 1 ANX 1 I Apoptosis antigen 1 APT1 I Apoptosis antigen ligand 1 APT1LG1 I Apoptosis-inducing factor AIF I ATP-binding cassette transporter 7 ABC7 I Attractin I Autoimmune regulator, AIRE AIRE I B-cell CLL/lymphoma 1 BCL1 I B-cell CLL/lymphoma 10 BCL10 I B-cell CLL/lymnphoma 3 BCL3 I B-cell CLL/lymphoma 4 BCL4 I B-cell CLL/lymphoma 5 BCL5 I B-cell CLL/lymphoma 6 BCL6 I B-cell CLL/lymphoma 7 BCL7 I B-cell CLL/lymphoma 8 BCL8 I B-cell CLL/lymphoma 9 BCL9 I beta 2 microglobulin B2M I Bradykinin receptor B1 I Bradykinin receptor B2 I Calcineurin A1 CALNA1 I Calcineurin A2 CALNA2 I Calcineurin A3 CALNA3 I Calcineurin B I Catalase CAT I CD1 CD1 I CD10 CD10 I CD100 CD100 I CD101 CD101 I CD103 CD103 I CD106 CD106 I CD107 CD107 I CD108 CD108 I CD109 CD109 I CD110 CD110 I CD111 CD111 I CD112 CD112 I CD113 CD113 I CD114 CD114 I CD115 CD115 I CD116 CD116 I CD117 CD117 I CD118 CD118 I CD119 CD119 I CD12 CD12 I CD120 CD120 I CD121 CD121 I CD122 CD122 I CD123 CD123 I CD124 CD124 I CD125 CD125 I CD126 CD126 I CD127 CD127 I CD128 CD128 I CD129 CD129 I CD13 CD13 I CD130 CD130 I CD131 CD131 I CD132 CD132 I CD133 CD133 I CD134 CD134 I CD135 CD135 I CD136 CD136 I CD137 CD137 I CD138 CDl38 I CD139 CD139 I CD14 CD14 I CD140 CD140 I CD141 CD141 I CD142 CD142 I CD143 CD143 I CD144 CD144 I CD145 CD145 I CD147 CD147 I CD148 CD148 I CD149 CD149 I CD15 CD15 I CD150 CD150 I CD151 CD151 I CD152 CD152 I CD153 CD153 I CD154 CD154 I CD155 CD155 I CD156 CD156 I CD157 CD157 I CD158 CD158 I CD159 CD159 I CD160 CD160 I CD161 CD161 I CD162 CD162 I CD163 CD163 I CD164 CD164 I CD165 CD165 I CD166 CD166 I CD17 CD17 I CD19 CD19 I CD2 CD2 I CD20 CD20 I CD22 CD22 I CD23 CD23 I CD24 CD24 I CD25 CD25 I CD26 CD26 I CD27 CD27 I CD28 CD28 I CD3 CD3 I CD30 CD30 I CD31 CD31 I CD33 CD33 I CD34 CD34 I CD36 CD36 I CD37 CD37 I CD38 CD38 I CD39 CD39 I CD4 CD4 I CD40 CD40 I CD41 CD41 I CD42 CD42 I CD43 CD43 I CD44 CD44 I CD45 CD45 I CD46 CD46 I CD47 CD47 I CD48 CD48 I CD5 CD5 I CD50 CD50 I CD52 CD52 I CD53 CD53 I CD55 CD55 I CD57 CD57 I CD58 CD58 I CD59 CD59 I CD6 CD6 I CD60 CD60 I CD63 CD63 I CD65 CD65 I CD66 CD66 I CD67 CD67 I CD68 CD68 I CD69 CD69 I CD7 CD7 I CD70 CD70 I CD71 CD71 I CD72 CD72 I CD73 CD73 I CD74 CD74 I CD75 CD75 I CD76 CD76 I CD77 CD77 I CD78 CD78 I CD79 CD79 I CD8 CD8 I CD80 CD80 I CD81 CD81 I CD83 CD83 I CD84 CD84 I CD85 CD85 I CD86 CD86 I CD88 CD88 I CD89 CD89 I CD9 CD9 I CD90 CD90 I CD91 CD91 I CD92 CD92 I CD93 CD93 I CD94 CD94 I CD96 CD96 I CD97 CD97 I CD98 CD98 I CD99 CD99 I Chemokine MCAF MCAF I Chemokine receptor CCR2 CCR2 I Chemokine receptor CCR3 CCR3 I Chemokine receptor CCR5 CCR5 I Chemokine receptor CXCR1 CXCR1 I Chemokine receptor CXCR2 CXCR2 I Chemokine receptor CXCR4 CXCR4 I Cholesterylester hydrolase I Chondritin Sulphate A—placental receptor I Cochlin COCH I Complement component C1 inhibitor C1NH I Complement component C1qa C1QA I Complement component C1qb C1QB I Complement component C1qg C1QG I Complement component C1r C1R I Complement component C1s C1S I Complement component C2 C2 I Complement component C3 C3 I Complement component C4A C4A I Complement component C4B C4B I Complement component C5 C5 I Complement component C6 C6 I Complement component C7 C7 I Complement component C8 C8 I Complement component C9 C9 I Complement component receptor 1 CR1 I Complement component receptor 2 CR2 I Complement component receptor 3 CR3 I Corticosteroid nuclear receptor I Cortisol receptor I C-reactive protein CRP I Cyclophilin I Cytokine-suppressive antiinflammatory CSBP1 I drug-binding protein 1 Cytokine-suppressive antiinflammatory CSBP2 I drug-binding protein 2 DAX1 nuclear receptor DAX1 I Endo-P-D-glucuronicase I Erythropoietin EPO I Erythropoietin receptor EPOR I Factor 1 (No. one) F1 I Factor B, properdin I Factor D I Factor H HF1 I Factor I (letter I) 1F I Factor III F3 I Factor IX F9 I Factor V F5 I Factor VII F7 I Factor VIII F8 I Factor X F10 I Factor XI F11 I Factor XII F12 I Factor XIII A & B F13A & F13B I Fc receptor I Follicular lymphoma variant FVT1 I translocation 1 Gastrointestinal tumor-associated GA733 I antigen 1 Growth-regulated protein precursor, GRO GRO I Haptoglobin, alpha 1 HPA1 I Haptoglobin, alpha 2 HPA2 I Haptoglobin, beta HPB I Heat shock protein, HSP60 I Heat shock protein, HSP70 I Heat shock protein, HSP90 I Heat shock protein, HSPA1 I Heat shock protein, HSPA2 I Hemopexin HPX I Heparin Cofactor II HCF2 I Hepatitis B virus integration site 1 HVBS1 I Hepatitis B virus integration site 2 HVBS6 I Histatin 1 I Histatin 2 I Histatin 3 HTN3 I HLA-B associated transcript 1 BAT1 I IC7 A and B I Immunoglobulin alpha (IgA) IGHA I Immunoglobulin gamma (IgG) 2 IGHG2 I Immunoglobulin delta (IgD) IGHD I Immunoglobulin epsilon (IgE) IGHE I Immunoglobulin E (IgE) reponsiveness IGER I gene Immunoglobulin E (IgE) serum IGES I concentration regulator gene Immunoglobulin heavy mu chain IGHM I Immunoglobulin J polypeptide IGJ I Immunoglobulin kappa constant region IGKC I Immunoglobulin kappa variable region IGKV I Intercellular adhesion molecule 1 ICAM1 I Intercellular adhesion molecule 2 ICAM2 I Intercellular adhesion molecule 3 ICAM3 I Interferon alpha IFNA1 I Interferon beta IFNB I Interferon gamma IFNG I Interferon gamma receptor 1 IFNGR1 I Interferon gamma receptor 2 IFNGR2 I Interferon regulatory factor 1 IRF 1 I Interferon regulatory factor 4 IRF4 I Interleukin(IL) 1, receptor IL1R I Interleukin(IL) 1, alpha IL1A I Interleukin(IL) 1, beta IL1B I Interleukin(IL) 10 IL10 I Interleukin(IL) 10 receptor IL10R I Interleukin(IL) 11 IL11 I Interleukin(IL) 11 receptor IL11R I Interleukin(IL) 12 IL12 I Interleukin(IL) 12 receptor, beta 1 IL12RB1 I Interleukin(IL) 13 IL13 I Interleukin(IL) 13 receptor IL13R I Interleukin(lL) 2 IL2 I Interleukin(IL) 2 receptor, alpha IL2RA I Interleukin(IL) 2 receptor, gamma IL2RG I Interleukin(IL) 3 IL3 I Interleukin(IL) 3 receptor IL3R I Interleukin(IL) 4 IL4 I Interleukin(IL) 4 receptor IL4R I Interleukin(IL) 5 IL5 I Interleukin(IL) 5 receptor IL5R I Interleukin(IL) 6 IL6 I Interleukin(IL) 6 receptor IL6R I Interleukin(IL) 7 IL7 I Interleukin(IL) 7 receptor IL7R I Interleukin(IL) 8 IL8 I Interleukin(IL) 8 receptor IL8R Interleukin(IL) 9 IL9 I Interleukin(IL) 9 receptor IL9R I Interleukin(IL) receptor antagonist 1 IL1RN, IL1RA I Kallikrein 3 KAK3 I Kininogen, High molecular weight KNG I Lectin, mannose-binding 1 LMAN1 I Lectin, mannose-binding 2 MBL2 I Leukin I Leukocyte-specific transcript 1 LST-1 I Leukotriene A4 hydrolase I Leukotriene B4 receptor I Leukotriene C4 receptor I Leukotriene D4/E4 receptor I LIM-Kinase 1 (LINK-1) I Lipocortin 1 ANX4 I Lipoprotein lipase LPL I Lipoprotein-associated coagulation factor LAC1 I Lipoxygenase 12 (platelets) LOG12 I Lipoxygenase 5 (leukocytes) I Lymphoblastic leukemia derived LYL1 I sequence 1 Lymphocyte-specific protein tyrosine LCK I kinase lymphotoxin Lysozyme LYZ I Macrophage activating factor MAF I Macrophage inflammatory protein-1 MIP1 I Macrophage inflammatory protein-1 I receptor Macrophage inflammatory protein-2 MIP2 I Macrophage inflammatory protein-2 I receptor Malignant proliferation, eosinophil gene MPE I Mannose binding protein MBP I MHC Class I:
A I MHC Class I:
B I MHC Class I:
C I MHC Class I:
LMP-2, LMP-7 I MHC Class I:
Tap 1 ABCR, TAP1 I MHC Class II:
DP HLA-DPB1 I MHC Class II:
DQ I MHC Class II:
DR I MHC Class II:
Tap2 TAP2, PSF2 I MHC Class II:
Complementation group A MHC2TA I MHC Class II:
Complementation group B rfxank I MHC Class II:
Complementation group C RFX5 I MHC Class II:
Complementation group D RFXAP I Monocyte chemoattractant protein 1 MCP1 I Myeloid leukemia factor-1 MLF1 I Myeloperoxidase MPO I N-acyl hydrolase I NADPH oxidase I Natural resistance-associated macrophage NRAMP1 I protein 1 NB6 I Neuronal apoptosis inhibitory protein NAIP I Neuronal molecule-1 I Neuronal molecule-1 receptor I Neutrophil cystolic factor 1 NCF1 I Neutrophil cystolic factor 2 NCF2 I Nuclear factor 1-kappa-B-like gene IKBL I Nuclear factor kappa beta NFKB I Peanut-like 1 PNUTL1 I Phagocytin I Phospholipase A2, group 10 PLA2G10 I Phospholipase A2, group 1B PLA2G1B I Phospholipase A2, group 2A PLA2G2A I Phospholipase A2, group 2B PLA2G2B I Phospholipase A2, group 4A PLA2G4A I Phospholipase A2, group 4C PLA2G4C I Phospholipase A2, group 5 PLA2G5 I Phospholipase A2, group 6 PLA2G6 I Phospholipase C alpha I Phospholipase C beta I Phospholipase C delta PLCD1 I Phospholipase C epsilon I Phospholipase C gamma PLCG1 I Platelet glycoprotein 1b, alpha GP1BA I Platelet glycoprotein 1b, beta GP1BB I Platelet glycoprotein 1b, gamma GP1BG I Platelet glycoprotein IX GP9 I Platelet glycoprotein V GP5 I Platelet-activating factor PAFAH1B1 or I acetylhydrolase 1B LIS1 Platelet-activating factor acetylhydrolase 2 PAFAH2 I Platelet-activating factor receptor PAFR I Poliovirus receptor PVR, PVS I Prekallikrein I Properdin P factor, complement PFC, PFD I Prostacyclin synthase I Prostaglandin 15-OH dehydrogenase HGPD;
PGDH I Prostaglandin D—DP receptor I Prostaglandin E1 receptor I Prostaglandin E2 receptor I Prostaglandin E3 receptor I Prostaglandin F—FP receptor I Prostaglandin F2 alpha receptor I Prostaglandin IP receptor I Protein C PROC I Protein C inhibitor PCI I Protein S PROS1 I Proteinase 3 I Prothrombin precursor F2 I SAP (SLAM-associated protein) SH2D1A I Severe combined immunodeficiency, type SC1DA I A (Athabascan) Signaling lymphocyte activation molecule SLAM I Sjoegren (Sjogren) syndrome antigen A1 SSA1 I SYK-related tyrosine kinase SRK I T-cell acute lymphocytic leukemia 1 TAL1 I T-cell acute lymphocytic leukemia 2 TAL2 I T-cell receptor, alpha TCRA I T-cell receptor, delta TCRD I Terminal deoxynucleotidyltransferase TDT I Thrombin receptor F2R I Thrombomodulin THBD I Thromboxane A synthase 1 TBXAS1 I Thromboxane A2 TXA2 I Thromboxane A2 receptor TBXA2R I Thy-1 T-cell antigen THY1 I Thymic humoral factor I Thymosin I Tip-associated protein TAP I Toll-like receptor 4 TLR4 I Tumour necrosis factor (TNF) receptor TRAF1 I associated factor 1 Tumour necrosis factor (TNF) receptor TRAF2 I associated factor 2 Tumour necrosis factor (TNF) receptor TRAF3 I associated factor 3 Tumour necrosis factor (TNF) receptor TRAF4 I associated factor 4 Tumour necrosis factor (TNF) receptor TRAF5 I associated factor 5 Tumour necrosis factor (TNF) receptor TRAF6 I associated factor 6 Tumour necrosis factor alpha TNFA I Tumour necrosis factor alpha receptor TNFAR I Tumour necrosis factor beta TNFB I Tumour necrosis factor beta receptor TNFBR I Tumour suppresssor gene DRA DRA I Uridine monophosphate kinase UMPK I Uridine monophosphate synthetase UMPS I Vimentin VIM I Wiskott-Aldrich syndrome protein WASP, THC I 17-ketosteroid reductase N Acetylcholine receptor, nicotinic, CHRNA1 N alpha A1 Acetylcholine receptor, nicotinic, CHRNA2 N alpha A2 Acetylcholine receptor, nicotinic, CHRNA3 N alpha A3 Acetylcholine receptor, nicotinic, CHRNA4 N alpha A4 Acetylcholine receptor, nicotinic, CHRNA5 N alpha A5 Acetylcholine receptor, nicotinic, CHRNA6 N alpha A6 Acetylcholine receptor, nicotinic, CHRNA7 N alpha A7 Acetylcholine receptor, nicotinic, beta 1 CHRNB1 N Acetylcholine receptor, nicotinic, beta 2 CHRNB2 N Acetylcholine receptor, nicotinic, beta 3 CHRNB3 N Acetylcholine receptor, nicotinic, beta 4 CHRNB4 N Acetylcholine receptor, nicotinic, epsilon CHRNE N Acetylcholine receptor, nicotinic, gamma CHRNG N Adenosine receptor A1 ADORA1 N Adenosine receptor A2A ADORA2A N Adenosine receptor A2B ADORA2B N Adenosine receptor A3 ADORA3 N Adenyl cyclase N Adrenergic receptor, alpha1 ADRA1 N Adrenergic receptor, alpha2 ADRA2 N Adrenergic receptor, beta1 ADRB1 N Adrenergic receptor, beta2 ADRB2 N Adrenergic receptor, beta3 ADRB3 N alpha thalassemia gene ATRX N alpha-synuclein SNCA N Amyloid beta (A4) precursor APBB1 N protein-binding, APBB 1 Amyloid beta A4 precursor protein APP N Amyloid beta A4 precursor-like protein APLP N Arginine vasopressin AVP N Arginine vasopressin receptor 1A AVPR1A N Arginine vasopressin receptor 1B AVPR1B N Arginine vasopressin receptor 2 AVPR2 N Aspartate receptor N Benzodiazepine receptor N beta-endorphin receptor N beta-synuclein SNCB N Calcitonin receptor/Calcitonin gene-related CALCR N peptide receptor Calcitonin/Calcitonin gene-related peptide CALCA N alpha Calcium channel, voltage-dependent, CACNA1F N alpha 1F subunit Calcium channel, voltage-dependent, CACNA1B N Alpha-B (CACNL1A5) Calcium channel, voltage-dependent, CACNA1C N Alpha-1C Calcium channel, voltage-dependent, CACNA1D N Alpha-1D Calcium channel, voltage-dependent, CACNA1E N Alpha-1E (CACNL1A6) Calcium channel, voltage-dependent, CACNA2 N Alpha-2/delta Calcium channel, voltage-dependent, CACNB1 N Beta 1 Calcium channel, voltage-dependent, CACNB3 N Beta 3 Calcium channel, voltage-dependent, CACNA1S N L type, alpha 1S subunit Calcium channel, voltage-dependent, CACNG2 N Neuronal, Gamma Calcium channel, voltage-dependent, CACNA1A N P/Q type, alpha 1A subunit Calcium channel, voltage-dependent, N T-type Calretinin CALB2 N Cannabinoid receptor CNR1 N Carnosinase N Cartilage oligomeric matrix protein COMP, EDM1, N PSACH Cartilage-hair hypoplasia gene CHH N Cellubrevin CEB N Ceroid lipofuscinosis neuronal 2 CLN2 N Ceroid lipofuscinosis neuronal 3 CLN3 N Ceroid lipofuscinosis neuronal 4 CLN4 N Ceroid lipofuscinosis neuronal 5 CLN5 N Ceroid lipofuscinosis neuronal 6 CLN6 N Cholecystokinin CCK N Cholecystokinin B receptor CCKBR N Corticosteroid binding globulin CBG N Cyclic nucleotide gated channel alpha 1, CNGA1 N CNGA1 Cyclic nucleotide gated channel alpha 3, CNGA3 N CNGA3 Cystic fibrosis transmembrane CFTR N conductance regulator, CFTR Deafness autosomal dominant 5 DFNA5 N Deafness dystonia peptide DDP N Diaphanous 1 DIAPH1 N Diaphanous 2 DIAPH2 N Dihydrolipoamide branched chain DBT N transacylase Dihydrolipoamide dehydrogenase DLD N Dihydrolipoamide succinyltransferase N Dopamine receptors D1 DRD1 N Dopamine receptors D2 DRD2 N Dopamine receptors D3 DRD3 N Dopamine receptors D4 DRD4 N Dopamine receptors D5 DRD5 N Dynorphin receptor N Endobrevin VAMP8 N Endothelin 1 EDN1 N Endothelin 2 EDN2 N Endothelin 3 EDN3 N Endothelin converting enzyme ECE1 N Endothelin receptor type A EDNRA N Endothelin receptor type B EDNRB N Fragile site, folic acid type, rare, FRAXA N fra(X) A Fragile site, folic acid type, rare, FRAXE N fra(X) E Fragile site, folic acid type, rare, FRAXF N fra(X) F GABA receptor, alpha 1 GABRA1 N GABA receptor, alpha 2 GABRA2 N GABA receptor, alpha 3 GABRA3 N GABA receptor, alpha 4 GABRA4 N GABA receptor, alpha 5 GABRA5 N GABA receptor, alpha 6 GABRA6 N GABA receptor, beta 1 GABRB1 N GABA receptor, beta 2 GABRB2 N GABA receptor, beta 3 GABRB3 N GABA receptor, gamma 1 GABRG1 N GABA receptor, gamma 2 GABRG2 N GABA receptor, gamma 3 GABRG3 N Galanin GAL N Galanin receptor GALNR1 N Gephyrin N Glial-cell derived neurotrophic factor N (GDNF) receptor Glial-cell derived neurotrophic factor, GDNF N GDNF Glutamate receptor 1 GLUR1 N Glutamate receptor 2 GLUR2 N Glutamate receptor 3 GLUR3 N Glutamate receptor 4 GLUR4 N Glutamate receptor 5 GLUR5 N Glutamate receptor 6 GLUR6 N Glutamate receptor 7 GLUR7 N Glutamate receptor, ionotropic, NMDAR1 N NMDA 1 Glutamate receptor, ionotropic, NMDAR2A N NMDA 2A Glutamate receptor, ionotropic, NMDAR2B N NMDA 2B Glutamate receptor, ionotropic, NMDAR2C N NMDA 2C Glutamate receptor, ionotropic, NMDAR2D N NMDA 2D Glycine receptor, alpha GLRA2 N Glycine receptor, beta N Glycine transporter GLYT N Guanine nucleotide-binding protein, alpha GNA11 N inhibiting activity polypeptide 1, GNA11 Guanine nucleotide-binding protein, alpha GNA12 N inhibiting activity polypeptide 2, GNA12 Guanine nucleotide-binding protein, alpha GNA13 N inhibiting activity polypeptide 3, GNA13 Guanine nucleotide-binding protein, alpha GNAS1 N stimulating activity polypeptide, GNAS1 Guanine nucleotide-binding protein, alpha GNAS2 N stimulating activity polypeptide, GNAS2 Guanine nucleotide-binding protein, alpha GNAS3 N stimulating activity polypeptide, GNAS3 Guanine nucleotide-binding protein, alpha GNAS4 N stimulating activity polypeptide, GNAS4 Guanine nucleotide-binding protein, alpha GNAT1 N transducing activity polypeptide, GNAT1 Guanine nucleotide-binding protein, alpha GNAT2 N transducing activity polypeptide, GNAT2 Guanine nucleotide-binding protein, alpha GNAO1 N activating activity polypeptide, GNAO Guanine nucleotide-binding protein, beta GNB3 N polypeptide 3 Guanine nucleotide-binding protein, GNG5 N gamma polypeptide 5 Guanine nucleotide-binding protein, q GNAQ N polypeptide Gustducin, alpha (taste-specific G protein) GDCA N H(+), K(+)—ATPase ATP4B N Hippocampal cholinergic neurostimulating HCNP N peptide, Histamine receptors, H1 N Histamine receptors, H2 N Histamine receptors, H3 N Inositol monophosphatase IMPA1 N Inositol polyphosphate 1-phosphatase INPP1 N Islet amyloid polypeptide IAPP N L1 cell adhesion molecule L1CAM N Luteinizing hormone-releasing hormone N Luteinizing hormone-releasing hormone N receptor Melatonin receptor 1A MTNR1A N Melatonin receptor 1B MTNR1B N Muscarinic receptor, M1 CHRM1 N Muscarinic receptor, M2 CHRM2 N Muscarinic receptor, M3 CHRM3 N Muscarinic receptor, M4 CHRM4 N Muscarinic receptor, M5 CHRM5 N Neurexin N Neurite growth-promoting factor 2 MDK N Neurite inhibitory protein N Neurokinin A NKNA N Neurokinin B NKNB N Neuropeptide Y NPY N Neuropeptide Y receptor Y1 NPY1R N Neuropeptide Y receptor Y2 NPY2R N Neurotensin NTS N Neurotensin receptor NTSR1 N Opioid receptor, delta OPRD1 N Opioid receptor, kappa OPRK1 N Opioid receptor, mu OPRM1 N Otoferlin OTOF N Oxytocin OXT N Oxytocin receptor OXTR N Parkin PARK2 N Pituitary adenylate cyclase activating PACAP N peptide Pituitary adenylate cyclase activating PACAP1R N peptide receptor Postsynaptic density-95 protein PSD95 N Potassium inwardly-rectifying channel J1 KCNJ1 N Potassium inwardly-rectifying channel J11 KCNJ11 N Potassium voltage-gated channel A1 KCNA1 N Potassium voltage-gated channel E1 KCNE1 N Potassium voltage-gated channel Q1 KCNQ1 N Potassium voltage-gated channel Q2 KCNQ2 N Potassium voltage-gated channel Q3 KCNQ3 N Potassium voltage-gated channel Q4 KCNQ4 N Potassium channel, subfamily K, KCNK1 N member 1 Potassium channel, subfamily K, KCNK2 N member 2 Potassium channel, subfamily K, KCNK3 N member 3 Potassium channel, calcium-activated, KCNN4 N Preproenkephalin PENK N Prion protein PRNP N Prodynorphin N Proopiomelanocortin POMC N Prosaposin PSAP N Proteolipid protein PLP N Purinergic receptor P1A1 N Purinergic receptor P1A2 N Purinergic receptor P1A3 N Purinergic receptor P2X, 1 P2RX1 N Purinergic receptor P2X, 2 P2RX2 N Purinergic receptor P2X, 3 P2RX3 N Purinergic receptor P2X, 4 P2RX4 N Purinergic receptor P2X, 5 P2RX5 N Purinergic receptor P2X, 6 P2RX6 N Purinergic receptor P2X, 7 P2RX7 N Purinergic receptor P2Y, 1 P2RX1 N Purinergic receptor P2Y, 2 P2RY2 N Purinergic receptor P2Y, 11 P2RY11 N Rabphilin N RAS-associated protein, RAB3A RAB3A N Rim N S100 calcium-binding protein A1 S100A1 N S100 calcium-binding protein A2 S100A2 N S100 calcium-binding protein A3 S100A3 N S100 calcium-binding protein A4 S100A4 N S100 calcium-binding protein A5 S100A5 N S100 calcium-binding protein A6 S100A6 N S100 calcium-binding protein A7 S100A7 N S100 calcium-binding protein A8 S100A8 N S100 calcium-binding protein A9 S100A9 N S100 calcium-binding protein B S100B N S100 calcium-binding protein P S100P N Secretase, alpha N Secretase, alpha N Secretase, beta N Secretase, gamma N Selectin E SELE N Selectin L SELL N Selectin P SELP N Serotonin receptor, 5HT1A HTR1A N Serotonin receptor, 5HT1B HTR1B N Serotonin receptor, 5HT1C HTR1C N Serotonin receptor, 5HT1D HTR1D N Serotonin receptor, 5HT1E HTR1E N Serotonin receptor, 5HT1F HTR1F N Serotonin receptor, 5HT2A HTR2A N Serotonin receptor, 5HT2B HTR2B N Serotonin receptor, 5HT2C HTR2C N Serotonin receptor, 5HT3 HTR3 N Serotonin receptor, 5HT4 HTR4 N Serotonin receptor, 5HT5 HTR5 N Serotonin receptor, 5HT6 HTR6 N Serotonin receptor, 5HT7 HTR7 N Sodium channel, non-voltage gated 1, SCNN1A N alpha Sodium channel, non-voltage gated 1, SCNN1B N beta Sodium channel, non-voltage gated 1, SCNN1G N gamma Sodium channel, voltage gated, type IV, SCN4A N alpha polypeptide Sodium channel, voltage gated, type V, SCN5A N alpha polypeptide Sodium channel, voltage-gated, type 1, SCN1B N beta polypeptide Somatostatin SST N Somatostatin receptor, SSTR1 SSTR1 N Somatostatin receptor, SSTR2 SSTR2 G Somatostatin receptor, SSTR3 SSTR3 N Somatostatin receptor, SSTR4 SSTR4 N Somatostatin receptor, SSTR5 SSTR5 N Spinocerebellar ataxia 8 gene SCA8 N Substance P N Synapsin 1a & 1b SYN1 N Synapsin 2a & 2b SYN2 N Synaptic vesicle amine transporter SVAT N Synaptic vesicle protein 2 SV2 N Synaptobrevin 1 SYB1 N Synaptobrevin 2 SYB2 N Synaptogyrin N Synaptophysin SYP N Synaptosomal-associated protein, 25KD SNAP25 N Synaptotagmin 1 SYT1 N Synaptotagmin 2 SYT2 N Syntaxin 1 STX1 N Tachykinin receptor, NK1R TACR1 N Tachykinin receptor, NK2R TACR2 N Tachykinin receptor, NK3R TACR3 N Thyrotropin releasing hormone TRH N Thyrotropin releasing hormone receptor TRHR N Transcription factor, TUPLE1 TUPLE1 N Tremor, essential 1 ETM1 N Tremor, essential 2 ETM2 N Tryptophan 2,3-dioxygenase TDO2 N Vacuolar proton pump, subunit 1 VPP1 N Vacuolar proton pump, subunit 3 VPP3 N Vasoactive intestinal polypeptide VIP N Vasoactive intestinal polypeptide receptor VIPR N Vesicular monoamine transporter 1 VMAT1 N Vesicular monoamine transporter 2 VMAT2 N Absent in melanoma 1 gene AIM1 G Acrosin ACR G Activin G Activin A receptor, type 2-like kinase 1 ACVRL1 G Activin A receptor, type 2B ACVR2B G Adenomatous polyposis coli tumour APC G supressor gene Adrenocorticotrophic hormnone (ACTH) ACTHR G receptor Aldosterone receptor MLR G Alkaptonuria gene AKU G alpha tectorin TECTA G alpha-actinin 2 ACTN2 G alpha-actinin 3 ACTN3 G Alpha-fetoprotein AFP G Amphiregulin AREG G Androgen receptor AR G Angiopoietin 1 ANGPT1 G Angiopoietin 2 ANGPT2 G Anti-Mullerian hormone AMH G Anti-Mullerian hormone type 2 receptor AMHR2 G AP-2, alpha TFAP2A G AP-2, beta TFAP2B G AP-2, gamma TFAP2C G Apical protein, xenopus laevis-like APXL G Apopain CPP32 G Archaete-scute homolog 1 ASH1 G Archaete-scute homolog 2 ASH2 G Astrotactin ASTN G Ataxia telangiectasia complementation ATD, ATDC G group D Ataxia telangiectasia gene, AT ATM G Ataxin 1 SCA1 G Ataxin 2 SCA2 G Ataxin 3 MJD G Atrial natriuretic peptide ANP G Atrial natriuretic peptide receptor A NPR1 G Atrial natriuretic peptide receptor B NPR2 G Atrial natriuretic peptide receptor C NPR3 G Atrophin 1 DRPLA G Azoospermia factor 1 AZF1 G Bagpipe homeobox, drosophila BAPX1 G homolog of, 1 BCL2-associated X protein BAX G BCL2-related protein A1 BCL2A1 G Beckwith-Wiedemann region 1A BWR1A G Bloom syndrome protein BLM G Bone morphogenetic protein, BMP1 BMP1 G Bone morphogenetic protein, BMP2 BMP2 G Bone morphogenetic protein, BMP3 BMP3 G Bone morphogenetic protein, BMP4 BMP4 G Bone morphogenetic protein, BMP5 BMP5 G Bone morphogenetic protein, BMP6 BMP6 G Bone morphogenetic protein, BMP7 BMP7 G Bone morphogenetic protein, BMP8 BMP8 G Brain derived neurotrophic factor BDNF G Brain derived neurotrophic factor (BDNF) BDNFR G receptor BRCA1-associated RING domain gene 1 BARD1 G Breakpoint cluster region BCR G Breast cancer 1 BRCA1 G Breast cancer 2 BRCA2 G Breast cancer, ductal, 1 BRCD1 G Breast cancer, ductal, 2 BRCD2 G Bruton agammaglobulinaemia tyrosine BTK G kinase Cadherin E CDH1 G Cadherin EP G Cadherin N CDH2 G Cadherin P CDH3 G Calbindin 1 CALB1 G Calbindin D9K CALB3 G Calmodulin 1 CALM1 G Calmodulin 2 CALM2 G Calmodulin 3 CALM3 G Calmodulin-dependant protein kinase II CAMK2A G Calnexin CANX G Cardiac-specific homeobox, CSX CSX G Caspase 1 CASP1 G Caspase 10 CASP10 G Caspase 2 CASP2 G Caspase 3 CASP3 G Caspase 4 CASP4 G Caspase 5 CASP5 G Caspase 6 CASP6 G Caspase 7 CASP7 G Caspase 8 CASP8 G Caspase 9 CASP9 G Catenin, alpha CTNNA1 G Catenin, beta CTNNB1 G Catenin, gamma G Cdc 25 phosphatase G Cdc2 CDC2 G CDX1 G CEA G Cell adhesion molecule, intercellular, ICAM1 G ICAM Cell adhesion molecule, leukocyte- LECAM1 G endothelial, LECAM (CD62) Cell adhesion molecule, liver, LCAM LCAM G Cell adhesion molecule, neural, NCAM1 NCAM1 G Cell adhesion molecule, neural, NCAM120 G NCAM120 Cell adhesion molecule, neural, NCAM2 NCAM2 G Cell adhesion molecule, platelet- PACAM1 G endothelial, PECAM Cell adhesion molecule, vascular, VCAM VCAM1 G c-erbB1 ERBB1 G c-erbB2 ERBB2 G c-erbB3 ERBB3 G c-erbB4 ERBB4 G Cholestasis, progressive familial FIC1 G intrahepatic 1 gene Chromogranin A CHGA G Ciliary neurotrophic factor (CNTF) CNTF G Ciliary neurotrophic factor (CNTF) CNTFR G receptor c-kit receptor tyrosine kinase G Cleavage signal-1 protein CS1 G Cleft palate gene CPX G Clusterin CLU G Cockayne syndrome gene, CKN1 CKN1 G Collapsin G Colony-stimulating factor 1 CSF1 G Colony-stimulating factor 1 receptor CSF1R G Colony-stimulating factor 2 CSF2 G Colony-stimulating factor 2 alpha receptor CSF2RA G Colony-stimulating factor 2 beta receptor CSF2RB G Colony-stimulating factor 3 CSF3 G Colony-stimulating factor 3 receptor CSF3R G Cone-rod homeobox-containing gene CRX G Contactin CNTN1 G Core-binding factor, alpha 1 CBFA1 G Core-binding factor, alpha 2 CBFA2 G Core-binding factor, beta CBFB G Creb binding protein CREBBP G c-src tyrosine kinase CSK G Cyclic AMP response element binding CREB G protein Cyclic AMP response element modulator CREM G Cyclic AMP-dependent protein kinase PKA G Cyclin A CCNA G Cyclin B CCNB G Cyclin C CCNC G Cyclin D CCND1 G Cyclin E CCNE G Cyclin F CCNF G Cyclin-dependent kinase 1 CDK1 G Cyclin-dependent kinase 10 CDK10 G Cyclin-dependent kinase 2 CDK2 G Cyclin-dependent kinase 3 CDK3 G Cyclin-dependent kinase 4 CDK4 G Cyclin-dependent kinase 5 CDK5 G Cyclin-dependent kinase 6 CDK6 G Cyclin-dependent kinase 7 CDK7 G Cyclin-dependent kinase 8 CDK8 G Cyclin-dependent kinase 9 CDK9 G Cyclin-dependent kinase inhibitor 1A CDKN1A G (P21, CIP1) Cyclin-dependent kinase inhibitor 1B CDKN1B G (P27, KIP1) Cyclin-dependent kinase inhibitor 1C CDKN1C G (P57, KIP2) Cyclin-dependent kinase inhibitor 2A CDKN2A G (p16) Cyclin-dependent kinase inhibitor 3 CDKN3 G Defender against cell death 1 DAD1 G Deleted in azoospermia DAZ G Deleted in colorectal carcinoma DCC G Deleted in malignant brain tumours 1 DMBT1 G Dentin sialophosphoprotein DSPP G Desert hedgehog, dhh G Disrupted meiotic cDNA 1, homolog DMC1 G Distal-less homeobox 1 DLX1 G Distal-less homeobox 2 DLX2 G Distal-less homeobox 3 DLX3 G Distal-less homeobox 4 DLX4 G Distal-less homeobox 5 DLX5 G Distal-less homeobox 6 DLX6 G Dynamin DNM1 G Dynein G E74-like factor 1, ELF1 ELF1 G EB1 G Empty spiracles (drosophila) homologue 1 EMX1 G Empty spiracles (drosophila) homologue 2 EMX2 G Endometrial bleeding-associated factor EBAF G Engrailed-1 EN1 G Engrailed-2 EN2 G Ephrin receptor tyrosine kinase A EPHA G Ephrin receptor tyrosine kinase B EPHB G Ephrin-A EFNA G Ephrin-B EFNB G Epidermal growth factor EGF G Epidermal growth factor receptor EGFR G Erythroid kruppel-like factor EKLF G Estrogen receptor ESR G Eukaryotic initiation translation factor EIF4E G EWS RNA-binding protein EWSR1 G Eyes absent 1 EYA1 G Eyes absent 2 EYA2 G Eyes absent 3 EYA3 G Fc fragment of IgG, high affinity IA, FCGR1A G receptor for Fc fragment of IgG, low affinity IIa, FCGR2A G receptor for (CD32) Fc fragment of IgG, low affinity IIIa, FCGR3A G receptor for (CD 16) Fertilin protein FTNB G Fibrillin 1 FBN1 G Fibrillin 2 FBN2 G Fibroblast growth factor FGF1 G Fibroblast growth factor receptor 1 FGFR1 G Fibroblast growth factor receptor 2 FGFR2 G Fibroblast growth factor receptor 3 FGFR3 G Fibronectin precursor FNI G Flightless-II, Drosophila homolog of FLII G Folic acid receptor FOLR G Follicle stimulating hormone receptor FSHR, ODG1 G Follicle stimulating hormone, FSH FSHB G Follistatin G Forkhead rhabdomyosarcoma gene FKHR G Forkhead transcription factor 10 FKHL10 G Forkhead transcription factor 14 FKHL14 G Forkhead transcription factor 7 FKHL7 G Frataxin FRDA G Fringe secreted protein, lunatic LFNG G Fringe secreted protein, manic MFNG G Fringe secreted protein, radical RFNG G Fukuyama type congenital muscular FCMD G dystrophy G/T mismatch binding protein GTBP, MSH6 G Galactosyltransferase 1 GT1 G Galactosyltransferase, alpha 1,3 GGTA1 G Galactosyltransferase, beta 3 B3GALT G Gastrin GAS G Gastrulation brain homeobox 2 GBX2 G GDP dissociation inhibitor 1 GDI1 G Gelsolin GSN G Geniospasm 1 GSM1 G Glioma chloride ion channel, GCC G Glucagon receptor GCGR G Glucagon-like peptide receptor 1 GLP1R G Glucocorticoid receptor GRL G Glypican 3 GPC3, SDYS G Gonadotropin releasing hormone GNRH G Gonadotropin releasing hormone receptor GNRHR G Goosecoid GSC G Growth arrest-specific homeobox GAX G Growth factor receptor-bound protein 2 GRB2 G Growth hormone 1 GH1 G Growth hormone 2 (placental) GH2 G Growth hormone receptor GHR G Growth hormone releasing hormone GHRH G (GHRH) Growth hormone releasing hormone GHRHR G receptor Growth/differentiation factor 5 GDF5 G GTP cylcohydrolase 1 GCH1 G GTPase-activating protein, GAP RASA1 G Hairless HR G Hela tumor suppression gene HTS1 G Heparin binding epidermal growth factor HBEGF G Hepatocyte growth factor HGF G High mobility group protein 1 HMG1 G High mobility group protein 2 HMG2 G High mobility group protein C HMG1C G High mobility group protein Y HMG1Y G Histone family H1 H1 G Histone family H2 H2 G Histone family H3 H3 G Histone family H4 H4 G HLH transcription factor HAND1 HAND1 G HLH transcription factor HAND2 HAND2 G Holoprosencephaly 1 HPE1 G Holoprosencephaly 2 HPE2 G Holoprosencephaly 3 HPE3 G Holoprosencephaly 4 HPE4 G Homeobox (HOX) gene A1 HOXA1 G Homeobox (HOX) gene A2 HOXA2 G Homeobox (HOX) gene A3 HOXA3 G Homeobox (HOX) gene A4 HOXA4 G Homeobox (HOX) gene A5 HOXA5 G Homeobox (HOX) gene A6 HOXA6 G Homeobox (HOX) gene A7 HOXA7 G Homeobox (HOX) gene A8 HOXA8 G Homeobox (HOX) gene A9 HOXA9 G Homeobox (HOX) gene A10 HOXA10 G Homeobox (HOX) gene A11 HOXA11 G Homeobox (HOX) gene A12 HOXA12 G Homeobox (HOX) gene A13 HOXA13 G Homeobox (HOX) gene B1 HOXB1 G Homeobox (HOX) gene B2 HOXB2 G Homeobox (HOX) gene B3 HOXB3 G Homeobox (HOX) gene B4 HOXB4 G Homeobox (HOX) gene B5 HOXB5 G Homeobox (HOX) gene B6 HOXB6 G Homeobox (HOX) gene B7 HOXB7 G Homeobox (BOX) gene B8 HOXB8 G Homeobox (HOX) gene B9 HOXB9 G Homeobox (HOX) gene C4 HOXC4 G Homeobox (HOX) gene C8 HOXC8 G Homeobox (HOX) gene C9 HOXC9 G Homeobox (HOX) gene C13 HOXC13 G Homeobox (HOX) gene D1 HOXD1 G Homeobox (HOX) gene D3 HOXD3 G Homeobox (HOX) gene D4 HOXD4 G Homeobox (HOX) gene D8 HOXD8 G Homeobox (HOX) gene D9 HOXD9 G Homeobox (HOX) gene D10 HOXD10 G Homeobox (HOX) gene D12 HOXD12 G Homeobox (HOX) gene D13 HOXD13 G Homeobox 11 HOX11 G Homeobox HB24 HLX1 G Homeobox HB9 HLXB9 G Homeobox, PROX1 PROX1 G Human atonal gene ATOH1 G Human chorionic gonadtrophin, hCG CG G Human placental lactogen CSH1 G Ikaros gene IKAROS G Indian hedgehog, ihh IHH G Inhibin, alpha INHA G Inhibin, beta A INHBA G Inhibin, beta B INHBB G Inhibin, beta C INHBC G Inositol 1,4,5-triphosphate receptor 1 ITPR1 G Inositol 1,4,5-triphosphate receptor 3 ITPR3 G Insulin INS G Insulin promotor factor 1 IPF1 G Insulin receptor INSR G Insulin receptor substrate-1 IRS1 G Insulin-like growth factor 1 IGF1 G Insulin-like growth factor 1 receptor IGF1R G Insulin-like growth factor 2 IGF2 G Insulin-like growth factor 2 receptor IGF2R G Integrin beta 1 ITGB1 G Integrin beta 2 ITGB2 G Integrin beta 3 ITGB3 G Integrin beta 4 ITGB4 G Integrin beta 5 ITGB5 G Integrin beta 6 ITGB6 G Integrin beta 7 ITGB7 G Integrin, alpha 1 ITGA1 G Integrin, alpha 2 ITGA2 G Integrin, alpha 3 ITGA3 G Integrin, alpha 4 ITGA4 G Integrin, alpha 5 ITGA5 G Integrin, alpha 6 ITGA6 G Integrin, alpha 7 ITGA7 G Integrin, alpha 8 ITGA8 G Integrin, alpha 9 ITGA9 G Integrin, alpha M ITGAM G Integrin, alpha X ITGAX G Janus kinase 1 JAK1 G Janus kinase 2 JAK2 G Janus kinase 3 JAK3 G Kallman syndrome gene 1 KAL1 G Kinectin KTN1 G Kinesin, heavy chain KNSL1 G Kinesin, light chain KNS2 G Lamin A/C LMNA G Laminin 5, alpha 3 LAMA3 G Laminin 5, beta 3 LAMB3 G Laminin 5, gamma 2 LAMC2 G Laminin M LAMM G Laminin receptor 1 LAMR1 G Latent transforming growth factor-beta LTBP2 G binding protein 2 Leptin LEP G Leptin receptor LEPR G Leukaemia inhibitory factor LIF G Leukaemia inhibitory factor receptor LIFR G LH/choriogonadotropin (CG) receptor LHCGR G LIM homeobox protein 1 LHX1 G LIM homeobox protein 2 LHX2 G LIM homeobox protein 3 LHX3 G LIM homeobox protein 4 LHX4 G LIM homeobox transcription factor 1, beta LMX1B G Limb girdle muscular dystrophy 1A LGMD1A G Limb girdle muscular dystrophy 1B LGMD1B G Limb girdle muscular dystrophy 2G LGMD2G G Limb girdle muscular dystrophy 2H LGMD2H G Limbic associated membrane protein LAMP G LIM-domain only protein 1 LMO 1 G LIM-domain only protein 2 LMO2 G LIM-domain only protein 3 LMO3 G LIM-domain only protein 4 LMO4 G Lipoma-preferred partner gene LPP G Luteinizing hormone, beta chain LHB G Lymphoid enhancer-binding factor LEF-1 G Lysosome-associated membrane protein 1 LAMP1 G Lysosome-associated membrane protein 2 LAMP2 G MAD (mothers against decapentaplegic, MADH2 G Drosophila) homologue 2 MAD (mothers against decapentaplegic, MADH3 G Drosophila) homologue 3 MAD (mothers against decapentaplegic, MADH4 G Drosophila) homologue 4 MADS box transcription-enhancer MEF2A G factor 2A MADS box transcription-enhancer MEF2B G factor 2B MADS box transcription-enhancer MEF2C G factor 2C MADS box transcription-enhancer MEF2D G factor 2D MAPK kinase 1 MAPKK1;
G MEK1 MAPK kinase 4 MAPKK4;
G MEK4;
SERK1 MAPK kinase 6 MAPKK6;
G MEK6 MAPKK kinase MAPKKK G Matrix Gla protein MGP G MAX-interacting protein 1 MXI1 G Menin MEN1 G Mesoderm-specific transcript MEST G Microphthalmia-associated transcription MITF G factor Midline 1 MID1 G Mismatch repair gene, PMSL1 PMS1 G Mismatch repair gene, PMSL2 PMS2 G Mitogen-activated protein (MAP) kinase MAPK G Motilin MLN G Msh homeobox homolog 1 MSX1 G Msh homeobox homolog 2 MSX2 G Multidrug resistance associated protein MRP G Mutated in colorectal cancers, MCC MCC G MutL homolog 1 MLH1 G MutS homolog 2 MSH2 G MutS homolog 3 MSH3 G Myelodysplasia syndrome 1 gene MDS1 G Myogenic factor 3 MYF3 G Myogenic factor 4 MYF4 G Myogenic factor 5 MYF5 G Na+, K+ ATPase, alpha ATP1A1 G Na+, K+ ATPase, beta 1 ATP1B1 G Na+, K+ ATPase, beta 2 ATP1B2 G Na+, K+ ATPase, beta 3 ATP1B3 G Necdin NDN G Nerve growth factor NGF G Nerve growth factor receptor NGFR G Neural retina-specific gene NRL G Neuregulin HGL G Neurofibromin 1 NF1 G Neurofibromin 2 NF2 G Neurotrophic tyrosine kinase receptor 1 NTRK1 G Neurotrophin 3 NTF3 or NT3 G Neurturin NRTN G Niacin receptor G Nibrin NBS1 G Nodal NODAL G Noggin NOG G Norrie disease protein NDP G Notch 1 NOTCH1 G Notch 2 NOTCH2 G Notch 3 NOTCH3 G Notch ligand—jagged 1 JAG1, AGS G Nuclear factor of activated T cells (NFAT) NFATC G complex, cytosolic Nuclear factor of activated T cells (NFAT) NFATP G complex, preexisting component Nuclear mitotic apparatus protein 1 NUMA 1 G Oligophrenin-1 OPHN1 G Oncogene abl1 abl1 G Oncogene abl2 G Oncogene akt1 G Oncogene akt2 AKT2 G Oncogene axl AXL G Oncogene bcl2 G Oncogene bcr/abl G Oncogene B-lym G Oncogene B-raf G Oncogene clk1 G Oncogene c-myc G Oncogene cot G Oncogene crk G Oncogene crk1 G Oncogene ect2 G Oncogene ELK1 ELK1 G Oncogene ELK2 ELK2 G Oncogene ems1 G Oncogene ERB G Oncogene ERB2 G Oncogene ERBA G Oncogene ERBAL2 G Oncogene ERG (early reponse gene) G Oncogene ETS1 G Oncogene ETS2 G Oncogene EVI1 EVI1 G Oncogene fes G Oncogene fgr G Oncogene fos FOS G Oncogene fps G Oncogene GLI1 GLI G Oncogene GLI2 GLI2 G Oncogene GLI3 GLI3 G Oncogene gro1 G Oncogene gro2 G Oncogene Ha-ras HRAS G Oncogene hsl G Oncogene hst FGF4 G Oncogene int1 WNT1 G Oncogene int2 FGF3 G Oncogene int3 Notch4 G Oncogene int4 WNT3 G Oncogenejun JUN G Oncogene KIT KIT, PBT G Oncogene LCO LCO G Oncogene l-myc G Oncogene lpsa G Oncogene lyn G Oncogene maf G Oncogene mas1 G Oncogene mcf2 G Oncogene mdm2 MDM2 G Oncogene mel G Oncogene met MET G Oncogene mos G Oncogene mpl G Oncogene MUM1 MUM1 G Oncogene myb MYB G Oncogene myc MYC G Oncogene n-myc G Oncogene N-ras (neuroblastoma v-ras) NRAS G Oncogene ovc G Oncogene pim1 G Oncogene pti-1sea G Oncogene pvt1 G Oncogene raf RAF G Oncogene ralb G Oncogene rel G Oncogene ret RET G Oncogene r-myc G Oncogene ros G Oncogene R-ras G Oncogene sis PDGFB G Oncogene ski G Oncogene sno G Oncogene spi1 G Oncogene src G Oncogene tc2l G Oncogene TEL ETV6 G Oncogene tim G Oncogenc vavtrk G Oncogene v-Ki-ras2 KRAS2 G Oncogene yes G Oncogene yuasa G Oncostatin M OSM G Oncostatin M receptor OSMR G Orexin OX G Orexin 1 receptor OX1R G Orexin 2 receptor OX2R G Orthodenticle (Drosophila) homolog 1 OTX1 G Orthodenticle (Drosophila) homolog 2 OTX2 G Osteonectin ON G Osteopontin OPN G Osteoprotegerin OPG G p21-activated kinase 3 PAK3 G Paired box homeotic gene 1 PAX1 G Paired box homeotic gene 2 PAX2 G Paired box homeotic gene 3 PAX3 G Paired box homeotic gene 6 PAX6 G Paired box homeotic gene 7 PAX7 G Paired box homeotic gene 8 PAX8 G Paired-like homeodomain transcription PITX2 G factor 2 Paired-like homeodomain transcription PITX3 G factor 3 Parathyroid hormone PTH G Parathyroid hormone receptor PTHR1 G Parathyroid hormone related-peptide PTHrP G Parathyroid hormone-like hormone PTHLH G Parvalbumin PVALB G Patched (Drosophila) homolog, PTCH PTCH G Phosphatase & tensin homolog PTEN G Phosphate regulating gene with PHEX G homologies to endopeptidases on the X chromosome Phosphatidylinositol glycan, class A PIGA G (paroxysmal nocturnal hemoglobinuria) Phosphatidylinositol transfer protein PITPN G Phosphodiesterase 1/nucleotide PDNP1 G pyrophosphatase 1 Phosphodiesterase 1/nucleotide PDNP2 G pyrophosphatase 2 Phosphodiesterase 1/nucleotide PDNP3 G pyrophosphatase 3 Phosphomannomutase 1 PMM1 G Phosphomannomutase 2 PMM2 G Phytanoyl-CoA hydroxylase PHYH G Platelet derived growth factor PDGF G Platelet derived growth factor receptor PDGFR G Poly(A) binding protein 2 PABP2 G POU domain, class 1, transcription POU1F1 G factor 1 (Pit1) POU domain, class 3, transcription POU3F4 G factor 4 POU domain, class 4, transcription POU4F3 G factor 3 Pre-B-cell leukemia transcription factor 1 PBX1 G Preproglucagon GCG;
GLP1;
G GLP2 Profibrinolysin G Progesterone receptor (RU486 binding PGR G receptor) Prohibitin PHB G Prolactin PRL G Prolactin receptor PRLR G Prolactin releasing hormone PRH G Proliferin PLF G Pro-melanin-concentrating hormone PMCH G Promyclocytic leukemia gene PML G Prophet of Pit1 PROP1 G Prostaglandin (PG) D synthase, PGDS E hematopoietic Prostaglandin isomerase G Prostaglandin-endoperoxidase synthase 2 PTGS2 G Prostate cancer anti-metastasis gene KAI1 KAI1 G Protein tyrosine phosphatase, non-receptor PTPN12 G type 12 RAD51, DNA repair protein RAD51 G RAD52, DNA repair protein RAD52 G RAD54, DNA repair protein RAD54 G RAD55, DNA repair protein RAD55 G RAD57, DNA repair protein RAD57 G Ras-G-protein RAS G Rathke pouch homeobox, RPX RPX G Receptor tyrosine kinase (RTK), Nsk2 NSK2 G Recombination activating gene 1 RAG1 G Recombination activating gene 2 RAG2 G Relaxin H1 RLN1 G Relaxin H2 RLN2 G Retinoblastoma 1 RB1 G Retinoic acid receptor, alpha RARA G Retinoic acid receptor, beta RARB G Retinoic acid receptor, gamma RARG G Retinoid X receptor, alpha RXRA G Retinoid X receptor, beta RXRB G Retinoid X receptor, gamma RXRG G Retinoschisis, X-linked, juvenile RS G Rhabdoid tumors SMARCB1 G RIGUI RIGUI G Ryanodine receptor 1, skeletal RYR1 G SA homolog SAH G Sal-like 1 SALL1 G Serine/threonine kinase 11 STK11 G Serine/threonine kinase 2 STK2 G Sex determining region Y, SRY SRY G Short stature homeobox SHOX G Sialoprotein, bone BSP G Signal transducer and activator of STAT1 G transcription 1 Signal transducer and activator of STAT2 G transcription 2 Signal transducer and activator of STAT3 G transcription 3 Signal transducer and activator of STAT4 G transcription 4 Signal transducer and activator of STAT5 G transcription 5 Sine oculis homeobox, drosophila, SIX1 G homolog 1 Sine oculis homeobox, drosophila, SIX2 G homolog 2 Sine oculis homeobox, drosophila, SIX5 G homolog 5 Slug protein G Smoothelin SMTN G Smoothened (Drosophila) homolog SMOH G Somatotrophin G Sonic hedgehog, SHH SHH G SOS1 guanine nucleotide exchange factor SOS1 G Spastic paraplegia 7 SPG7 G Sperm adhesion molecule SPAM1 G Sperm protamine P1 PRM1 G Sperm protaminc P2 PRM2 G Split hand/foot malformation gene DSS1 G SRY-box 10 SOX10 G SRY-box 11 SOX11 G SRY-box 3 SOX3 G SRY-box 4 SOX4 G SRY-box 9 SOX9 G Stem cell factor SCF G Steroid hormone receptor responsive DNA G elements Stromal derived factor 1 SDF1 G Sulfamidase SGSH G Sulfonylurea receptor SUR G Suppression of tumorigenicity 3 gene ST3 G Suppression of tumorigenicity 8 gene ST8 G Surfeit 1 SURF1 G Syndecan 1 SYND1 G Syndecan 2 SYND2 G Syndecan 3 SYND3 G Syndecan 4 SYND4 G Synovial sarcoma gene 1 SSX1 G Synovial sarcoma gene 2 SSX2 G Talin TLN G TATA binding protein TBP G TATA binding protein associated TAF2A G factor 2A TATA binding protein associated TAF2C2 G factor 2C2 TATA binding protein associated TAF2E G factor 2D TATA binding protein associated TAF2F G factor 2F TATA binding protein associated TAF2H G factor 2H TATA binding protein associated TAF2I G factor 2I TATA binding protein associated TAF2J G factor 2J TATA binding protein associated TAF2K G factor 2K T-BOX 1 TBX1 G T-BOX 2 TBX2 G T-BOX 3 TBX3 G T-BOX 4 TBX4 G T-BOX 5 TBX5 G T-BOX 6 TBX6 G Testis-specific protein Y TSPY G Thrombopoietin THPO G Thrombospondin THBS1 G Thymopoietin TMPO G Thyroglobulin TG G Thyroid hormone receptor, alpha THRA G Thyroid hormone receptor, beta THRB G Thyroid peroxidase TPO G Thyroid receptor auxiliary protein TRAP G Thyroid-stimulating hormone receptor TSHR G Thyroid-stimulating hormone, alpha TSHA G Thyroid-stimulating hormone, beta TSHB G Thyrotroph embryonic factor TEF G Thyrotropin releasing hormone TRH G Thyrotropin releasing hormone receptor TRHR G TIE receptor tyrosine kinase TIE-1 G Torticollis, keloids, cryptorchidism and TKCR G renal dysplasia gene G Transcription factor 1, hepatic TCF1 G Transcription factor 2, hepatic TCF2 G Transcription factor 3 TCF3 G Transcription factor binding to IGHM TFE3 G enhancer 3 Transcription termination factor, RNA TTF1 G polymerase 1 G Transcription termination factor, RNA TTF2 G polymerase 2 G Transcription termination factor, RNA TTF3 G polymerase 3 G Transferrin TF G Transferrin receptor TFRC G Transforming growth factor, alpha TGFA G Transforming growth factor, beta 2 TGFB2 G Transforming growth factor, beta induced TGFB1 G Transforming growth factor, beta TGFBR2 G receptor 2 Transglutaminase 1 TGM 1 G Transglutaminase 2 TGM2 G Transglutaminase 4 TGM4 G Translocation in renal carcinoma on TRC8 G chromosome 8 gene G Treacle gene TCOF1 G Tubby-like protein 1 TULP 1 G Tuberous sclerosis 1 TSC1 G Tuberous sclerosis 2 TSC2 G Tumor susceptibility gene 101 TSG101 G Tumour protein p53 TP53, P53 G Tumour protein p63 TP63 G Tumour protein p73 TP73 G Tumour protein, translationally- TPT1 G controlled 1 Twist (Drosophila) homolog TWIST G Ubiquitin G Ubiquitin B UBB G Ubiquitin C UBC G Ubiquitin carboxyl-terminal esterase L1 UCHL1 G Ubiquitin fusion degeneration 1-like UFD1L G Vascular endothelial growth factor VEGF G Vasoinhibitory peptide G Vitamin B12-binding (R) protein G Vitamin D receptor VDR G v-myc avian myclocytomatosis viral MYC G oncogene homolog G Von Hippel-Lindau gene VHL G Werner syndrome helicase WRN G Wilms tumour gene 1 WT1 G Wilms tumour gene 2 WT2 G Wilms tumour gene 4 WT4 G Winged helix nude WHN G Wingless family, wnt2 WNT2 G Wingless family, wnt4 WNT4 G Wingless family, wnt5 WNT5 G Wingless family, wnt7 WNT7 G Wingless family, wnt8 WNT8 G Wnt inhibitory factor, WIF-1 WIF1 G Wolf-Hirschhorn syndrome candidate WHSC1 G 1 gene X (inactive)-specific transcript XIST G X-ray repair gene XRCC9 G YY1 transcription factor YY1 G Zona pellucida glycoprotein 1 ZP11 G Zona pellucida glycoprotein 2 ZP2 G Zona pellucida glycoprotein 3 ZP3 G Zona pellucida receptor tyrosine kinase ZRK G Zonadhesin ZAN G KEY TO ‘PROTEIN FUNCTION’ COLUMN E ENZYME T TRANSPORT & STORAGE S STRUCTURAL I IMMUNITY N NERVOUS TRANSMISSION G GROWTH & DIFFERENTIATION

26 more elements

Genostics

Life of this patent

Genostics

Life of this patent

Abstract

Claims34