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US 2003/0198968 A1Published application
Polymer-coated substrates for immobilization of biomolecules and cells
AssigneeBeckman Coulter, Inc.
InventorRobert S. Matson
Life of this patent
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AssigneeBeckman Coulter, Inc.
InventorRobert S. Matson
Estimating the term…
Methods for preparing a substrate for the arraying and immobilizing of biomolecules or cells are described. The methods include providing a solid support and depositing by a chemical plasma-mediated polymerization process a polymeric coating on the surface. The polymeric coating comprises at least one pendant functional group capable of attaching a biomolecule or a cell. A material of the polymeric coating is preferably selected in such a way that its surface properties enhance binding between the pendant group and the biomolecule or cell. A substrate for the immobilization of biomolecules and cells is also provided. The substrate comprises a solid support made of a polymeric material. The solid support has at least one first pendant functional group suitable for attaching a first biomolecule or a first cell on its surface. The substrate further comprises a polymeric coating deposited on the surface of the substrate. The polymeric coating increases the attachment of the first biomolecule or the first cell to the first functional group.
A method of preparing a substrate for the arraying of biomolecules or cells comprising the steps of:
A substrate for immobilizing a biopolymer or cell, the substrate comprising:
A method of attaching biomolecules and cells to a solid support comprising:
A bioarray prepared by a method comprising the steps of:
Dependencies are inferred from the claim text.