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AssigneeCouncil of Scientific and Industrial Research
InventorsSuman Preet Singh Khanuja, Suchi Srivastava, Tiruppadiripuliyur Ranganathan Santha Kumar, Madan Mohan Gupta, Arvind Kumar Tripathy, Monika Singh, Janak Raj Bahl, Raj Kishori Lal, Mahendra Pandurang Darokar, Ajit Kumar Shasany, Sushil Kumar
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The present invention relates a hexane bioactive fraction and obtained from the roots of an aromatic plant named Vetiveria zizanioides commonly found in India for inhibiting the growth of drug resistant bacterial infections in humans and animals; also relates to a pharmaceutical composition comprising the bioactive extract with other additives for inhibiting the growth of drug resistant bacterial infections in humans and animals and a process for the isolation of said bioactive extract
A bioactive hexane fraction named CIM 109 obtained from the plant Vetiveria zizaniodes having inhibitory activity against multi drug resistant bacterial pathogens.
A pharmaceutical composition for inhibiting the growth of the bacterial pathogens, comprising effective amount of bioactive fraction named CIM-109 or partially purified extract or lyophilised extract, obtained from the plant Vetiveria zizaniodes.
A pharmaceutical composition useful for treating fuloroquinolone resistant bacterial infections including enteric and systemic infections, said composition comprising 10 to 50% by wt of root extract of vetiver, 0.4 to 1% by wt of citric acid, 10 to 20% by wt of calcium carbonate, 10 to 20% by wt of magnesium hydroxide gel, 20 to 60% by weight of lactose and optionally comprising other pharmaceutically acceptable additives.
A method of treating patent with bacterial infection said method comprising administering a pharmaceutically effective dosage of bioactive fraction or a formulation comprising bioactive fraction or lyophilised extract of plant Vetiveria zizaniodes thereof to the patent.
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