Polynucleotides encoding antigenic HIV type B and/or type C polypeptides, polypeptides and uses thereof
OwnerJan zur Megede, Susan Barnett +1inventors
InventorsJan zur Megede, Susan Barnett, Ying Lian
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Abstract
The present invention relates to polynucleotides encoding immunogenic HIV polypeptides. Uses of the polynucleotides in applications including immunization, generation of packaging cell lines, and production of HIV polypeptides are also described. Polynucleotides encoding antigenic HIV polypeptides are described, as are uses of these polynucleotides and polypeptide products therefrom, including formulations of immunogenic compositions and uses thereof.
Claims58
A synthetic polynucleotide encoding two or more immunogenic HIV polypeptides, wherein at least two of said polypeptides are derived from different HIV subtypes.
The method of claim 69, wherein said mammal is a human.
Dependencies are inferred from the claim text.