Method of treating onychomycosis with urea and an antioxidant
AssigneeBradley Pharmaceuticals, Inc.
InventorsBradley P. Glassman, Dileep Bhagwat, Daniel Glassman
Life of this patent
Estimating the term…
Abstract
A method of treating onychomycosis is described which includes administration of a topical formulation containing an effective amount of urea and an antioxidant to an infected area around a nail of a patient.
Claims17
A method of treating onychomycosis comprising administering to the nail area of a patient in need thereof a composition comprising:
- (a) about 10 to about 60 wt-% urea;
- (b) about 0.1 to about 20 wt-% of an antioxidant, and the balance being dermatologically acceptable excipients.
A method of treating onychomycosis comprising administering to the nail area of a patient in need thereof a composition comprising:
- (a) about 10 to about 40 wt-% urea;
- (b) about 0.1 to about 20 wt-% of an antioxidant;
- (c) about 5.5 to about 20 wt-% petrolatum or a synthetic or semi-synthetic hydrocarbon, or a semi-solid mixture thereof;
- (d) about 10 to about 20 wt-% of a liquid petrolatum or a synthetic or semi-synthetic oleaginous liquid fraction, or a mixture thereof;
- (e) about 0.25 to about 2 wt-% of a C16-18 aliphatic straight or branched chain fatty alcohol or fatty acid, or a mixture thereof;
- (f) about 1 to about 5 wt-% propylene glycol;
- (g) about 1 to about 3 wt-% glyceryl stearate;
- (h) about 0.01 to about 0.5 wt-% xanthan gum;
- and
- (i) the balance being water.
A method of treating onychomycosis comprising administering to the nail area of a patient in need thereof a composition comprising:
- (a) about 10 to about 40 wt-% urea;
- (b) about 0.1 to about 20 wt-% of an antioxidant;
- (c) about 5.5 to about 20 wt-% petrolatum or a synthetic or semi-synthetic hydrocarbon, or a semi-solid mixture thereof;
- (d) about 10 to about 20 wt-% of a liquid petrolatum or a synthetic or semi-synthetic oleaginous liquid fraction, or a mixture thereof;
- (e) about 0.25 to about 2 wt-% of a C16-18 aliphatic straight or branched chain fatty alcohol or fatty acid, or a mixture thereof;
- (f) about 1 to about 5 wt-% propylene glycol;
- (g) about 1 to about 3 wt-% glyceryl stearate;
- (h) about 0.01 to about 0.5 wt-% xanthan gum;
- (i) about 0.05 to about 30 wt-% of a mixture of a carbomer and triethanolamine;
- and
- (j) the balance being water.
Dependencies are inferred from the claim text.