Synergistic mixtures of o-phenylphenol and other nitrogen and aldehyde microbiocides

#This invention relates to synergistic mixtures of o-phenylphenol and/or its sodium salt with glutaraldehyde and/or nitrogen-containing microbiocides (antimicrobials) and the use of the synergistic combinations in industrial applications.

#O-phenylphenol and Sodium orthophenylphenate (separately or collectively sometimes herein known as “OPP”, orthophenolphenol or o-phenylphenol and/or its sodium salt) are known and used extensively as antimicrobial agents in various industrial applications such as preservation of various materials including paints and adhesives as well as to control unwanted microorganisms found in various process waters such as cooling water, paper mills and petroleum production process waters.

#The contamination of various products with microbiological growth has led to the study and application of large classes of preservatives, antimicrobial compositions, and microbiocides to inhibit or prevent such contamination. Industrial process waters also have been studied and treated extensively. Preservatives are used in a broad range of products including but not limited to adhesives, cosmetics and toiletries, disinfectants and sanitizers, leather, metalworking fluids, paints and coatings, plastics and resins, latex polymers, textiles and wood. Failure to preserve these products adequately will result in spoilage and loss of the materials to be preserved and will result in an economic loss. Similarly, microbiological growths can have dire consequences if process waters are not adequately treated. Process waters include but are not limited to: industrial recirculating water, paper products—paper, petroleum production and leather tanning. Process waters are of concern because when fouled with biofilms that develop from the indigenous microbes present, biofilms may develop into thick gelatinous like masses. Slime is produced by a wide range of bacteria, fungi, and yeast. Slime will interfere with the process resulting in a loss of heat transfer, corrosion and fouling.

#This example shows synergistic activity between OPP and dodecylguanidine hydrochloride when fed simultaneously in a bacterial consortium in water at pH 5.0 and 8.0. 1 DGH* & NaOPP @ pH 5.5 1 DGH* & NaOPP @ pH 8.0 2 *DGH—Dodecylguanidine Hydrochloride

#2 ADBAC* & NaOPP @ pH 5.5 3 ADBAC* & NaOPP @ pH 8.0 4 *ADBAC—N-Alkyl (60% C14, 30% C16, 5% C12, 5% C18) dimethyl benzyl ammonium chloride

#The example shows synergistic activity between OPP and cis-1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride when fcd simultaneously in a bacterial consortium in synthetic water at pH 5.0 and 8.0. 3 CTAC* & NaOPP @ pH 5.5 5 CTAC* & NaOPP @ pH 8.0 6 *CTAC—cis-1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride