Method for improving the quality of sperm for artificial insemination of animals
AssigneeID-Lelystad, Instituut voor Dierhouderij en Diergezondheid B.V.
InventorsJacoba Johanna Matthijs-Rijsenbilt, Henri Woelders
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Abstract
A method and composition for artificial insemination. The method involves artificially inseminating the subject with sperm, wherein the sperm is combined or coadministered with an inhibitor of phosphodiesterase and preferably a soluble salt of an earth alkaline metal. The composition comprises phosphodiesterase inhibitor or a functional equivalent thereof, a soluble salt of an earth alkaline metal and sperm. The method and composition reduce the recruitment of polymorphonuclear neutrophils.
Claims20
A method for artificially inseminating a subject, comprising:
- administering an inseminate comprising sperm and an inhibitor of phosphodiesterase to the subject.
A method for elongating the functional life span of sperm, said method comprising:
- admixing or co-administering the sperm with an inhibitor of phosphodiesterase inhibitor.
A method for reducing the recruitment of polymorphonuclear neutrophils during an artificial insemination process, said method comprising:
- artificially inseminating a subject with a composition comprising sperm and an inhibitor of phosphodiesterase.
A method of reducing the phagocytosis of sperm during an artificial insemination process, said method comprising:
- artificially inseminating a subject with a composition comprising sperm and an inhibitor of phosphodiesterase.
An adjuvant for inseminating a subject, said adjuvant comprising:
- an inhibitor of phosphodiesterase inhibitor;
- and
- a soluble salt of an earth alkaline metal.
Dependencies are inferred from the claim text.