Bioengineered vascular graft support prostheses
AssigneesOrganogenesis, Inc., Duke University School of Medicine
InventorsGinger A. Abraham, Robert M. Carr JR., Tam Huynh, Per Otto Hagen, Mark Davies
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Abstract
The invention is directed to bioengineered vascular graft support prostheses prepared from cleaned tissue material derived from animal sources. The bioengineered graft prostheses of the invention are prepared using methods that preserve cell compatibility, strength, and bioremodelability of the processed tissue matrix. The bioengineered graft prostheses are used for implantation, repair, or for use in a mammalian host.
Claims18
A bioremodelable prosthesis comprising a collagen tube comprising at least one layer of processed tissue matrix of crosslinked submucosal collagen of small intestine.
A bioremodelable prosthesis comprising a collagen tube comprising at least one layer of processed tissue matrix of crosslinked submucosal collagen of small intestine, wherein the prosthesis functions as a remodeling template for the ingrowth of host cells, wherein the prosthesis is pliable, suturable, non-creeping, semi-permeable, and non-porous, and wherein the prosthesis is sterilized.
A bioremodelable external vein support comprising a collagen tube comprising at least one layer of processed tissue matrix of crosslinked submucosal collagen of small intestine.
A neuron growth tube comprising a collagen tube comprising at least one layer of processed tissue matrix of crosslinked submucosal collagen of small intestine.
Dependencies are inferred from the claim text.