Venlafaxine besylate
AssigneeSynthon BV
InventorsRolf Keltjens, Johannes Jan Platteeuw, Juan Cucala Escoi, Inocencia Margallo Lana, Frantisek Picha, Montserrat Gallego Luengo
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Abstract
Venlafaxine besylate compounds provide certain advantages over venlafaxine hydrochloride and are useful in forming pharmaceutical compositions and n treating venlafaxine-treatable diseases and conditions. Venlafaxine besylate can be easily formulated into an extended release dosage form including a hydrogel tablet as well as other matrix-based tablet compositions. A preferred tablet making process involves hot melt granulation.
Claims49
A venlafaxine besylate compound.
A pharmaceutical composition comprising a venlafaxine besylate compound and at least one pharmaceutically acceptable excipient.
A method for treating a venlafaxine-treatable disease or condition, which comprises administering to a patient in need thereof an effective amount of a venlafaxine besylate compound.
A process, which comprises:
- mixing venlafaxine besylate and a molten fusible carrier to form a partially melted mass;
- and
- cooling said partially melted mass to form a solidified product.
Dependencies are inferred from the claim text.