Composition comprising camptothecin or a camptothecin derivative and a topoisomerase II inhibitor for the treatment of cancer
OwnerMarie Christine Bisseryinventor
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Abstract
The present invention relates to therapeutic associations for the treatment of cancer, comprising an effective amount of a camptothecin, or a camptothecin derivative, with an effective amount of a topoisomerase II inhibitor, such as doxorubicin, daunorubicin, or etoposide, and methods of using such therapeutic associations.
Claims20
A therapeutic pharmaceutical composition, comprising an effective amount of camptothecin, or a camptothecin derivative, in combination with an effective amount of a topoisomerase II inhibitor for the treatment of solid tumors.
A therapeutic pharmaceutical composition, comprising an effective amount of CPT-11, in combination with an effective amount of a topoisomerase II inhibitor for the treatment of solid tumors.
A synergistic therapeutic pharmaceutical composition, comprising an effective amount at least two agents, wherein at least one agent is CPT-11, in combination with an effective amount of at least one second agent, wherein said second agent is doxorubicin, for the treatment of solid tumors.
A method of treating a solid tumor, comprising administering an effective amount of camptothecin, or a camptothecin derivative, as a first agent, in combination with administration of an effective amount of a topoisomerase II inhibitor as a second agent, wherein the agents are administered simultaneously, semi-simultaneously, or separately.
Dependencies are inferred from the claim text.