Antimicrobial peptides
AssigneeThe University of Melbourne
InventorsEric Charles Reynolds, Stuart Geoffrey Dashper, Neil Martin O'Brien-Simpson, Gert Hoy Talbo, Marina Malkoski
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Abstract
The present invention provides antimicrobial peptides. The peptides are non-glycosylated, less than about 100 amino acids in length, and include an amino acid sequence selected from: AVESTVATLEAΣPEVIESPPE (SEQ ID NO:3), AVESTVATLEDΣPEVIESPPE (SEQ ID NO:4), AVESTVATLEASPEVIESPPE (SEQ ID NO:5), AVESTVATLEDSPEVIESPPE (SEQ ID NO:6), DMPIQAFLLYQQPVLGPVR (SEQ ID NO:7), and conservative substitutions therein. These peptides can be produced synthetically; however, they can most conveniently be derived from casein.
Claims10
An antimicrobial peptide, the peptide being non-glycosylated, less than about 100 amino acids and including an amino acid sequence selected from the group consisting of:
- 24 AVESTVATLEAΣPEVIESPPE, (SEQ. ID. NO. 1) AVESTVATLEDΣPEVIESPPE, (SEQ. ID. NO. 2) AVESTVATLEASPEVIESPPE, (SEQ. ID. NO. 3) AVESTVATLEDSPEVIESPPE, (SEQ. ID. NO. 4) DMPIQAFLLYQQPVLGPVR. (SEQ. ID. NO. 5)
- and conservative substitutions therein.
Dependencies are inferred from the claim text.