Genes expressed in treated foam cells
AssigneeIncyte Genomics, Inc.
InventorsThomas Mikita, Dov Shiffman, J. Gordon Porter, Matthew R. Kaser
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Abstract
The invention relates to isolated polynucleotides, purified polypeptides, and compositions comprising pluralities of polynucleotides that are differentially expressed when foam cells are treated with oxidized low-density lipoprotein and LPS as associated with atherosclerosis. The invention also presents the use of the polynucleotides as elements on a substrate and provides methods for using the polynucleotides and polypeptides.
Claims20
A combination comprising a plurality of polynucleotides wherein the polynucleotides are SEQ ID NOs:1-127 and the complements of SEQ ID NOs:1-127.
A purified polynucleotide having a nucleic acid sequence selected from SEQ ID NOs:51, 52, 54, 79, 85, 102, 106, and 119 or the complements of SEQ ID NOs:51, 52, 54, 79, 85, 102, 106, and 119.
A purified polypeptide comprising an amino acid sequence of SEQ ID NOs:154 or 155.
Dependencies are inferred from the claim text.