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AssigneesWilliam Henry Campbell, Charles E. Skinner, Yung K. Kim
InventorsWilliam Henry Campbell, Yung K. Kim, Charles E. Skinner
Estimating the term…
Multi-layered macromolecules wherein the layers are covalently bonded together and wherein the macromolecules are covalently bonded to solid particulate substrates, methods for the preparation of such compositions, and methods for their uses in a multitude of end use applications ranging from the purification of waste chemical and metal process streams to the separation and identification of proteins, peptides, and oligionucleotides.
A multi-layered macromolecule comprising a base macromolecule chemically bonded to a solid particulate substrate wherein the base macromolecule is selected from the group consisting of:
A process of preparing a multi-layered macromolecule, said process comprising:
A process for preparing a multi-layered macromolecule, said process comprising:
A process of preparing a multi-layered macromolecule, said process comprising:
A process of preparing a multi-layered macromolecule, said process comprising:
A process of preparing a multi-layered macromolecule, said process comprising:
Dependencies are inferred from the claim text.
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Dendritic macromolecules: dendrimers
Characterised by the carrier, support or substrate used for impregnation or coating: inorganic carriers, supports or substrates
Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond: involving a…
Having a well defined chemical structure: the functional group or the linking, spacer or anchoring group as a whole comprising at least one of the…
Term end not estimated
This invention deals with multi-layered macromolecules that are chemically bonded to solid particulate substrates, methods for the preparation of such compositions, and methods for their uses in a multitude of end use applications ranging from the purification of waste chemical and metal process streams to the separation and identification of proteins, peptides, and oligionucleotides.
Since the decade of the nineteen eighties there has been a large volume of information reported on macromolecules, most specifically, the macromolecules that are dendritic in nature, and those that are hyperbranched.
Dendrimers are described as globular, nano-scale macromolecules consisting of two or more tree-like dendrons, emanating from a single central atom or atomic group called the core. They are comprised of branch cells that are the main building blocks of dendritic structures, that is, three-dimensional analogues of repeat units in classical linear polymers, that must contain at least one branch juncture, and that are organized in mathematically precise architectural arrangements, that give rise to a series of regular radially concentric layers, called generations (G) around the core. Dendrimers must contain at least three different types of branch cells including a core, interior cells, and surface or exterior cells.
FIG. 1 is an illustration of a base macromolecule.
FIG. 2 is an illustration of a PANAM repeating unit of FIG. 1.
FIG. 3 is an illustration of the reaction scheme of the silane bonding agent with the silica substrate.
What is disclosed herein is a first embodiment of this invention that is a multi-layered macromolecule comprising a base macromolecule chemically bonded to a solid particulate substrate wherein the base macromolecule is selected from the group consisting of dendrimers and hyperbranched polymers. The base macromolecule is surmounted by at least one additional layered macromolecule to form at least one chemically bonded layer on the base macromolecule. The layered macromolecule is also selected from the group consisting of dendrimers and hyperbranched polymers.
In another embodiment of this invention there is a process for preparing a multi-layered macromolecule. The process comprises (I) providing a solid particulate substrate capable of reacting with a first lot of a silane bonding agent and (II), contacting the solid particulate substrate with the first lot of silane bonding agent and allowing the solid particulate substrate to react with the first lot of silane bonding agent to form a product.
Then, in step (III), the product thus formed in step (II) is then contacted with a first lot of macromolecule selected from the group consisting of dendrimers and hyperbranched polymers wherein the macromolecule and the product from step (II) are allowed to react with each other. Thereafter, in step (IV), the product from step (III) is contacted with a second lot of silane bonding agent and then the second lot of silane bonding agent and the product from step (III) are allowed to react with each other. In step (V), the process requires providing a second lot of macromolecule and step (VI) provides for contacting the second lot of macromolecule with a third lot of silane bonding agent and allowing the third lot of silane bonding agent and the second lot of base macromolecule to react to form a reactive product.