Medicinal herbal extract carpediol for treating depression
AssigneeSwedish Herbal Institute
InventorsGeorg Wikman, Alexander Panossian
Life of this patent
Estimating the term…
Abstract
The present invention is directed to anti-depressive activity of Crassulaceae special extracts, Carpediol, containing 2-(4-hydroxyphenyl)ethyl-β-d-glucopyranoside or 3-[6-o-(α-1-arabinopyranosyl)-β-d-glucopyranosyl)-β-d-glucopyranosyl]-oxy-1-phenylpropene in mammals, to method of preparation and analysis of these extract, as well to safety of their usage in combination with other drugs.
Claims20
A method for treating a symptom of depression comprising administering to a person in need thereof a composition comprising an extract of a plant belonging to Crassulaceae.
A pharmaceutically acceptable composition comprising a standardized extract of a plant belonging to Crassulaceae comprising 2-(4-Hydroxyphenyl)ethyl-β-D-glucopyranoside or 3-[6-O-(α-L-arabinopyranosyl)-β-D-glucopyranosyl]oxy-1-phenylpropene.
A pharmaceutically acceptable tablet comprising a composition which comprises an extract of a plant belonging to Crassulaceae comprising 2-(4-Hydroxyphenyl)ethyl-β-D-glucopyranoside or 3-[6-O-(α-L-arabinopyranosyl)-β-D-glucopyranosyl]-oxy-1-phenylpropene.
A method for treating a symptom of depression comprising administering to a person in need thereof, a composition comprising 2-(4-Hydroxyphenyl)ethyl-β-D-glucopyranoside or 3-[6-O-(α-L-arabinopyranosyl)-β-D-glucopyranosyl]-oxy-1-phenylpropene, and a pharmaceutically acceptable carrier thereof.
A method for preparing a composition comprising an extract of Crassulaceae for treating a symptom of depression, which comprises:
- a) dispersing plant matter of said Crassulaceae in an alcohol;
- b) heating said dispersed plant matter,
- c) separating the alcohol solution from said plant matter,
- d) evaporating the alcohol solution to obtain spissum,
- e) dissolving the spissum in a liquid solution,
- f) extracting the liquid solution of step e) with a salt of an acid,
- g) extracting the liquid solution of step f) with an alcohol solution, and
- i) evaporating the alcohol solution of step g) to obtain said extract.
Dependencies are inferred from the claim text.