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US 2003/0194427 A1Published application
System of treating myopathic & neuropathic diseases
AssigneeNone recorded
InventorAnuthep Benja-Athon
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AssigneeNone recorded
InventorAnuthep Benja-Athon
Estimating the term…
A system of treating myopathic and neuropathic diseases comprises the delivery of neurotoxins to the muscles and nerves in the peripheral nervous and central nervous systems. The delivery of the neurotoxins is into or through the skin in human or animal. The system utilizes the uptake system, anterograde and retrograde axonal transports of neurons in the aforementioned nervous systems. The delivery system comprises of emulsifier, skin patch and jet injection. The chemicals are the amino acids, polypeptides, neurotoxins such as the botulinum toxins and venoms.
A system of delivering means for altering the neurochemistry of the neurons in the peripheral nervous system and central nervous system of a human and an animal wherein said neurons have the first neural endings and receptors in the skin or in a first organ system of said human and animal, wherein said neurons have the second neural endings and receptors, axons and dendrites in the ganglion and central nervous system, and wherein said method for delivering in said neurons utilizes the uptake system, anterograde and retrograde axonal transports of said neurons comprises:
The skin patch according to claim 4 comprises said means for altering the neurochemistry, an emulsifier means for retaining said means for altering the neurochemistry, and an emulsifier means for releasing said means for altering the neurochemistry by diffusion down a chemical gradient into said skin to said first neural endings and receptors.
The neurotoxins according to claim 16 are the botulinum toxins.
The neurotoxins according to claim 16 are the venoms.
A system of of delivering means for modulating the neurotransmitters and the function of the organelles in the neurons, presynaptic and postsynaptic sites in the peripheral nervous system and central nervous system that are involved in neuropathy, neuropathic disorders including pains, itches in a human and an animal wherein members of said neurons have the first endings and receptors in the skin and a first organ system of said human and animal, wherein said neurons have the second endings, axons, dendrites and cell bodies in the ganglia, peripheral and central nervous systems, and wherein said means for delivering utilizes the uptake system, anterograde and retrograde axonal transports of said neurons comprises:
Dependencies are inferred from the claim text.
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Magnetotherapy: in combination with another treatment
Continuous direct currents: apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or…
Electrotherapy
Term end not estimated
A system comprises three methods of delivering therapeutic neurotoxins, myotoxins and venoms to an organ system in the treatment of various diseases in human and animal.
The first objective of the present invention is to provide a system for treating many diseases whose effective treatments are not known.
The second objective of the present invention is to provide a system for treating diseases related to the disorders and disorders of an organ system in a human or animal.
FIG. 1 is the schematic illustration of the present invention.
FIG. 2 is the schematic detail illustration of the present invention.
FIG. 1 shows the system 1 of the present invention. System 1 comprises three methods of delivery or deposition of exogenous therapeutic chemicals 2 (ETC) as represented by dark dots into the skin 3 and other organs 4 within skin 3 such as blood vessels or deep to skin 3 such as muscles, glands, soft and bony tissues in a human or an animal.
In skin 3 or other organs 4 within skin 3 or deep to skin 3, there are afferent and efferent neurons 5. Neurons 5 are sensory, autonomic and motor nerves having the first neural endings and 6 and receptors 7 in the skin, organs 4 within or deep to skin 3 such as muscular, visceral and pelvic organs.
Going toward the central nervous system, neurons 5 have the second neural endings, receptors, axons, dendrites and cell bodies 8 in the afferent nerve ganglion 9 and same 10 in the autonomic nerve ganglion 11 in the peripheral nervous system (PNS) and endings 12, presynaptic and postsynaptic receptors, axons and dendrites 13 in the central nervous system (CNS) 14. At the ganglion, spinal cord and brain levels, endings, receptors, axons and dendrites 8, 10, 12 and 13 form numerous and extensive neural connections.