Systems for delivering agents into targeted tissue of a living being
AssigneeKensey Nash Corporation
InventorsJohn E. Nash, Douglas G. Evans, David M. Hoganson
Life of this patent
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Abstract
A system for accessing targeted tissue within the living being and introduction of particles at select locations into the myocardium and other select tissues. The system includes an instrument and a plurality of flowable particles to be delivered by the instrument via an externally applied force. The particles to the tissue may include one or more of pharmaceuticals, biologically active agents, radiopaque materials, etc.
Claims43
A system for vascularizing the cardiac tissue of a living being to cause the formation of lumens in communication with the being's arterial system, said system comprising a delivery instrument and a flowable agent, said flowable agent comprising a plurality of small particles for introduction into the cardiac tissue, said delivery instrument being arranged to introduce said particles at an entry situs at or adjacent the cardiac tissue by imparting a particle-moving force to said particles, said system being arranged to generate said particle moving force external to the being to cause said particles to pass directly through contiguous tissue to target cardiac tissue located remotely from said entry situs without any mechanical means carrying said particles through said contiguous tissue, whereupon said particles directly enter said target cardiac tissue.
A system for treating cardiac tissue of a living being to affect the conduction of electrical signals in the cardiac tissue, said system comprising a delivery instrument and a flowable agent, said flowable agent comprising a plurality of small particles for introduction into the cardiac tissue, said delivery instrument being arranged to introduce said particles at an entry situs at or adjacent the cardiac tissue by imparting a particle-moving force to said particles, said system being arranged to generate said particle moving force external to the being to cause said particles to pass directly through contiguous tissue to target cardiac tissue located remotely from said entry situs without any mechanical means carrying said particles through said contiguous tissue, whereupon said particles directly enter said target cardiac tissue.
A system for treating cardiac tissue of a living being to affect the conduction of nerve signals in the cardiac tissue, said system comprising a delivery instrument and a flowable agent, said flowable agent comprising a plurality of small particles for introduction into the cardiac tissue, said delivery instrument being arranged to introduce said particles at an entry situs at or adjacent the cardiac tissue by imparting a particle-moving force to said particles, said system being arranged to generate said particle moving force external to the being to cause said particles to pass directly through contiguous tissue to target cardiac tissue located remotely from said entry situs without any mechanical means carrying said particles through said contiguous tissue, whereupon said particles directly enter said target cardiac tissue.
A system for treating targeted internal tissue of a living being to produce a beneficial effect for the being, said system comprising a delivery instrument and a flowable agent, said flowable agent comprising a plurality of small particles for introduction into the targeted internal tissue, said delivery instrument being arranged to introduce said particles at an entry situs at or adjacent the targeted internal tissue by imparting a particle-moving force to said particles, said system being arranged to generate said particle moving force external to the being to cause said particles to pass directly through contiguous tissue to the targeted internal tissue located remotely from said entry situs without any mechanical means carrying said particles through said contiguous tissue, whereupon said particles directly enter said targeted cardiac tissue.
Dependencies are inferred from the claim text.