Arrangement for the treatment of barrett's esophagus
AssigneeCynosure, Inc.
InventorsJames H. Boll, George Cho
Life of this patent
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Abstract
A method for the treatment of Barrett's Esophagus of a patient having endothelial esophageal complications. The treatment comprises connecting a wavelength specific light source to an elongated light guide having a distal end, the light guide arranged within a lumen of a steerable endoscope, guiding the endoscope into the esophagus of the patient, energyzing the light source, and manipulating the distal end of the light source onto a target on the endothelial complications inside of the patient's esophagus for the selective thermolysis of the target in the esophagus, thereby reverting the red secretory esophageal lining to a normal lining.
Claims18
A method for the treatment of Barrett's Esophagus to reverse abnormal columnar epithelial cells and secretory lining in the esophagus of a patient having red secretory esophageal lining complications, comprising:
- connecting a wavelength specific optical radiation energy source to an elongated wave guide having a distal end, said wave guide arranged within a lumen of a steerable endoscope;
- guiding said endoscope into the esophagus of the patient;
- energyzing said optical energy source to generate an optical radiation treatment beam;
- manipulating said distal end of said wave guide onto a target on said endothelial complications inside of said esophagus for the selective thermolysis of said target in said esophagus by said optical radiation treatment beam;
- causing said red secretory esophogeal lining to revert to normal tissue, wherein said optical radiation treatment beam has a fluence range of 4-1000 J/cm2.
A method for the treatment of Barrett's Esophagus to reverse abnormal columnar epithelial cells and secretory lining in the esophagus of a patient having red secretory esophageal lining complications, comprising:
- connecting a wavelength specific optical radiation energy source to an elongated wave guide having a distal end, said wave guide arranged within a lumen of a steerable endoscope;
- guiding said endoscope into the esophagus of the patient;
- energyzing said optical energy source to generate a beam of light energy;
- manipulating said distal end of said light source onto said red secretory lining comprising said endothelial complications inside of said esophagus for the selective thermolysis of said red secretory lining in said esophagus;
- causing said red secretory esophogeal to revert to a normal non-secretory “whitish” tissue by maintenance of said energyzing of said optical energy source, wherein said optical radiation has a fluence range of 4-1000 J/cm2 and is inversely proportional to its spot size.
A method for the treatment of Barrett's Esophagus to reverse abnormal columnar epithelial cells and secretory lining in the esophagus of a patient having red secretory esophageal lining complications, comprising:
- connecting a wavelength specific optical radiation energy source to an elongated wave guide having a distal end, said wave guide arranged within a lumen of a steerable endoscope;
- guiding said endoscope into the esophagus of the patient;
- energyzing said optical energy source to generate a beam of light energy;
- manipulating said distal end of said light source onto said red secretory lining comprising said endothelial complications inside of said esophagus for the selective thermolysis of said red secretory lining in said esophagus;
- causing said red secretory esophageal to revert to a normal “whitish” tissue by maintenance of said energyzing of said optical energy source, wherein said optical radiation has a fluence range of 4-1000 J/cm2 and is inversely proportional to its spot size;
- wherein said spot size of said beam of light energy has a range of between 1 mm. to 10 mm. in diameter, and said optical radiation energy source comprises a pulsed dye laser having a wavelength of about 580-600 nm;
- and wherein said distal end of said optical radiation energy source is an optical coupler.
Dependencies are inferred from the claim text.