Crystalline pharmaceutical
AssigneeAbbott Laboratories
InventorsDaniel A. Dickman, Sanjay Chemburkar, James J. Fort, Rodger F. Henry, David Lechuga-Ballesteros, Yuping Niu, William Porter
Life of this patent
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Abstract
New crystalline forms of lopinavir are disclosed.
Drawings
Claims23
A crystalline hydrated form of lopinavir.
A substantially pure crystalline hydrated form of lopinavir.
A solvated crystalline form of lopinavir with a peak in the solid state infrared spectrum at a position within the range 1661-1673 cm−1, a peak in the solid state infrared spectrum at a position within the range 1645-1653 cm−1 and a peak in the solid state infrared spectrum at a position within the range 1619-1629 cm−1.
A substantially pure solvated crystalline form of lopinavir with a peak in the solid state infrared spectrum at a position within the range 1661-1673 cm−1, a peak in the solid state infrared spectrum at a position within the range 1645-1653 cm−1 and a peak in the solid state infrared spectrum at a position within the range 1619-1629 cm−1.
A crystalline form of lopinavir with a peak in the solid state infrared spectrum at a position within the range 1655-1662 cm−1.
A crystalline form of lopinavir with a peak in the solid state infrared spectrum at a position within the range 1655-1662 cm−1 and a peak in the solid state infrared spectrum at a position within the range 1636-1647 cm−1.
A substantially pure crystalline form of lopinavir with a peak in the solid state infrared spectrum at a position within the range 1655-1662 cm−1.
A substantially pure crystalline form of lopinavir with a peak in the solid state infrared spectrum at a position within the range 1655-1662 cm−1 and a peak in the solid state infrared spectrum at a position within the range 1636-1647 cm−1.
A solvated crystalline form of lopinavir with a peak in the solid state infrared spectrum at a position within the range 1655-1662 cm−1.
A solvated crystalline form of lopinavir with a peak in the solid state infrared spectrum at a position within the range 1655-1662 cm−1 and a peak in the solid state infrared spectrum at a position within the range 1636-1647 cm−1.
A substantially pure solvated crystalline form of lopinavir with a peak in the solid state infrared spectrum at a position within the range 1655-1662 cm−1.
A substantially pure solvated crystalline form of lopinavir with a peak in the solid state infrared spectrum at a position within the range 1655-1662 cm−1 and a peak in the solid state infrared spectrum at a position within the range 1636-1647 cm−1.
A non-solvated crystalline form of lopinavir.
A substantially pure non-solvated crystalline form of lopinavir.
Dependencies are inferred from the claim text.