Method of using cyclooxygenase inhibitors and antimuscarinic agents
OwnerEbrahim Versiinventor
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Abstract
The present invention provides a method for the use of a cyclooxygenase-2 inhibitor, alone or in combination with an anti-muscarinic agent, for the treatment or prophylaxis of a urinary incontinence condition in a subject in need of such treatment or prevention, comprising administering to the subject an effective amount of the cyclooxygenase-2 inhibitor and, optionally, the anti-muscarinic agent.
Claims48
A method for the treatment or prophylaxis of a urinary incontinence condition in a subject in need of such treatment or prophylaxis, comprising administering to the subject a treatment- or prophylaxis-effective amount of a cyclooxygenase inhibitor or pharmaceutically acceptable salt or prodrug thereof.
A method for the treatment or prophylaxis of a urinary incontinence condition in a subject in need of such treatment or prophylaxis, comprising administering to the subject an amount of
- an anti-muscarinic agent, and
- an amount of a cyclooxygenase inhibitor or pharmaceutically acceptable salt or prodrug thereof,
- wherein the amount of the anti-muscarinic agent and the amount of the cyclooxygenase inhibitor together comprise a urinary incontinence condition treatment- or prophylaxis-effective amount of the anti-muscarinic agent and the cyclooxygenase inhibitor.
A pharmaceutical composition comprising:
- an amount of an anti-muscarinic agent,
- an amount of a cyclooxygenase inhibitor or prodrug thereof, and
- an amount of a pharmaceutically acceptable carrier.
Use of:
- an amount of an anti-muscarinic agent,
- an amount of a cyclooxygenase inhibitor or prodrug thereof, and
- a pharmaceutically acceptable carrier,
- in the preparation of the pharmaceutical composition to be used in the treatment or prophylaxis of a urinary incontinence condition.
A kit comprised of:
- an amount of an anti-muscarinic agent in a dosage formulation, and
- an amount of a cyclooxygenase inhibitor or prodrug thereof in a separate dosage formulation.
A method for the treatment or prophylaxis of interstitial cystitis in a patient in need of such treatment or prophylaxis, comprising administering to the patient:
- an amount of an anti-muscarinic agent, and
- an amount of a cyclooxygenase inhibitor or prodrug thereof,
- wherein the amount of the anti-muscarinic agent and the amount of the cyclooxygenase inhibitor together comprise a interstitial cystitis condition treatment- or prophylaxis-effective amount of the anti-muscarinic agent and the cyclooxygenase inhibitor.
Dependencies are inferred from the claim text.