Unsaturated derivatives at the 4-position of 6-tert-butyl-1,1-dimethylindane and their use in human and veterinary medicine and in cosmetics

Unsaturated derivatives at the 4-position of 6-tert-butyl-1,1-dimethylindane corresponding to the following general formula:

• 20
• in which:
• X represents:
• (i) either a divalent radical of following formula:
• 21
• and Y then represents a divalent radical of following formula:
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• (ii) or a divalent radical of formula:
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• and Y then represents either a divalent radical corresponding to the divalent radical of formula (b) above or one of the divalent radicals of following formula:
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• Z being —O—, —S— or
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• R1 represents —CH3, —(CH2)p—OR4, —(CH2)p—COR9 or —S(O)6—R5,
• p being 0, 1, 2 or 3,
• t being 0, 1 or 2,
• R2 represents H or lower alkyl,
• R3 represents H, lower alkyl or —COR7,
• R4 represents H, lower alkyl, —COR7, aryl, aralkyl, mono- or polyhydroxyalkyl, or a polyether radical,
• R5 represents H, lower alkyl, —OR3 or
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• R6 represents H or lower alkyl,
• R7 represents lower alkyl,
• R9 represents H, alkyl, alkenyl, alkynyl, aryl, aralkyl, mono- or polyhydroxyalkyl, a sugar residue or an amino acid residue,
• r′ and r″, which are identical or different, represent H, lower alkyl, —COR7, aryl, a sugar residue or an amino acid residue or r′ and r″, taken together, form a heterocycle, and the salts of the compounds of formula (I), when R1 represents a carboxylic acid functional group, and the geometrical and optical isomers of the compound of formula (I).