Melanin concentrating hormone receptor ligands

A compound of the formula:

• 19
• or a pharmaceutically acceptable salt thereof wherein:
• Q represents a group of the Formula:
• 20
• wherein A is C1-C5 alkylene optionally mono-, di, or trisubstituted with substitutuents independently chosen from C1-C3 alkyl, C1-C3 alkoxy, halogen, halo(C1-C3)alkyl, halo(C1-C3)alkoxy, hydroxy, amino, and mono- or di(C1-C3)alkylamino;
• R1, R2, R3, R4, R5, R6, R7, and R8 are the same or different and represent hydrogen, halogen, cyano, nitro, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C1-C6 alkoxy, C1-C6 alkylthio, hydroxy, amino, mono or di(C1-C6)alkyl amino, halo(C1-C6)alkyl, halo(C1-C6)alkoxy, C1-C6 alkanoyl, C1-C6 alkoxycarbonyl, —COOH, —SO2NH2, mono or dialkylsulfonamido, —C(O)NH2, or mono or di(C1-C6)alkylcarboxamido;
• R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, and R19 independently represent hydrogen or C1-C6 alkyl;
• W is nitrogen or C—Ra where Ra represents hydrogen, hydroxy, C1-C6 alkoxy, C1-C6 alkyl or cyano;
• X represents halogen, cyano, nitro, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C1-C6 alkoxy, C1-C6 alkylthio, hydroxy, amino, mono or di(C1-C6)alkylamino, halo(C1-C6)alkyl, halo(C1-C6)alkoxy, C1-C6 alkanoyl, C1-C6 alkoxycarbonyl, —COOH, —CONH2, mono- or di(C1-C6)alkylcarboxamido, —SO2NH2, mono or di(C1-C6)alkylsulfonamido;
• or
• X represents phenyl which may be optionally substituted with up to five substituents, which aree the same or different and are selected from the group consisting of hydrogen, halogen, cyano, nitro, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C1-C6 alkoxy, C1-C6 alkylthio, hydroxy, amino, mono or di(C1-C6)alkyl amino, halo(C1-C6)alkyl, halo(C1-C6)alkoxy, C1-C6 alkanoyl, C1-C6 alkoxycarbonyl, —COOH, —CONH2, mono- or di-(C1-C6)alkylcarboxamido, —SO2NH2, and mono or di(C1-C6)alkylsulfonamido;
• Y is oxygen, sulfur, —S(O)—, or —SO2—;
• and
• Z is C1-C6 alkyl or mono, di or trifluoromethyl.