Carbamoyl tetrahydropyridine derivatives
AssigneeTaisho Pharmaceutical Co., Ltd.
InventorsAtsuro Nakazato, Taketoshi Okubo, Toshihito Kumagai, Kazuyuki Tomisawa
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AssigneeTaisho Pharmaceutical Co., Ltd.
InventorsAtsuro Nakazato, Taketoshi Okubo, Toshihito Kumagai, Kazuyuki Tomisawa
Estimating the term…
Carbamoyl tetrahydropyridine derivatives represented by the formula: 1 [in the formula, R1 and R2 are identical or different, and each represents a hydrogen atom, a C1-C5 alkyl group, or the like; Y1—Y2 represents (R4)C═C(R5), (R6)C═N, N═N, (R7) N—CO, or N═C(R8); X1, X2, and X3 are identical or different, and each represents a hydrogen atom, a halogen atom, or the like; R3, R41 R5, and R6are identical or different, and each represents a hydrogen atom or an alkyl group; R7 represents a hydrogen atom, a C1-C5 alkyl group, or the like; and R8 represents a hydrogen atom or a carbamoyl group] or a pharmaceutically acceptable salt thereof, and intermediates for the preparation thereof are provided. The derivatives described above are effective for diseases which are believed to involve CRF.
A carbamoyl tetrahydropyridine derivative represented by the formula:
A pyrrolopyrimidine derivative represented by the formula:
A pyrrole derivative represented by the formula:
A 4- or 5-carbamoyl-1,2,3,6-tetrahydropyridine, represented by the formula:
Dependencies are inferred from the claim text.