Method of hormonal therapy
OwnerThomas W. Leonard, R. Forrest Waldoninventors
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Abstract
The present invention combines the administration of estrogens with the administration of non-aromatizing androgens to treat frailty in women undergoing estrogen replacement therapy.
Claims41
A method of treating sexual dysfunction and/or frailty in a woman comprising:
- administering a therapeutic amount of a non-aromatizing androgenic compound in a daily dose in an amount of 0.1 to 10 mg of said non-aromatizing androgenic compound equivalent to oral dosages of oxandrolone of about 0.1 to 10 mg.
A method of treating frailty in a woman undergoing estrogen replacement therapy, the method comprising administering to said woman, continuously and uninterruptedly, a therapeutically effective amount of both estrogen and a non-aromatizing androgen in daily dosages, wherein said estrogenic compound is equivalent to oral estradiol dosages of about 0.05 to 3 mg, and said non-aromatizing androgenic compound is equivalent to oral dosages of about 0.1 to 10 mg of an androgenic compound.
A method of treating frailty in a woman undergoing estrogen replacement therapy comprising cyclically administering to said woman an estrogenic compound, and continuously and uninterruptedly administering to said woman a non-aromatizing androgenic compound.
A method of treating weakness in a woman undergoing estrogen replacement therapy comprising continuously and uninterruptedly administering daily dosages of a therapeutically effective amount of an estrogenic compound equivalent to estradiol dosages of about 0.05 to 3 mg, and continuously and uninterruptedly administering to said woman a therapeutically effective amount of a non-aromatizing androgenic compound equivalent to oral dosages of oxandrolone of about 0.1 to 10 mg.
A method of treating frailty in a woman undergoing estrogen replacement therapy comprising cyclically administering to said woman a non-aromatizing androgenic compound.
A method of treating frailty in a woman undergoing estrogen replacement therapy comprising continuously and uninterruptedly administering daily dosages of a therapeutically effective amount of an estrogenic compound equivalent to estradiol dosages of about 0.05 to 3 mg, and continuously and uninterruptedly cyclically administering to said woman a therapeutically effective amount of a non-aromatizing androgenic compound equivalent to oral oxandrolone dosages of about 0.1 to 10 mg.
A method of treating sexual dysfunction and/or frailty in a woman comprising:
- administering a therapeutic amount of an androgenic compound in a daily dose in an amount of 0.1 to 10 mg of said androgenic compound, wherein said androgenic compound comprises at least 50% of a non-aromatizing androgenic compound.
A method of treating sexual dysfunction and/or frailty in a woman comprising:
- administering a therapeutic amount of a non-aromatizing androgenic compound in a dosing cycle in an amount of 0.1 to 10 mg of said non-aromatizing androgenic compound equivalent to oral dosages of oxandrolone of about 0.1 to 10 mg.
Dependencies are inferred from the claim text.