Methods of differentiating dementing diseases
AssigneesMaruha Corporation, Japan Science and Technology Corporation, Osaka Bioscience Institute
InventorsMitsuhito Mase, Hiroya Nakau, Takashi Inui, Naomi Eguchi, Yoshihiro Urade, Kosuke Seiki, Hiroshi Oda, Hiroshi Nakajima, Nobuyuki Sato
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Abstract
The present invention relates to methods for differentiating demential diseases comprising measuring the concentration of human lipocalin-type prostaglandin D synthase in a sample of a body fluid collected from a subject and kits for differentiating demential diseases comprising an antibody specific to human lipocalin-type prostaglandin D synthase.
Claims8
(Amended) A method for differentiating a demential disease comprising measuring the concentration of human lipocalin-type prostaglandin D synthase (L-PGDS) in a sample of a body fluid collected from a subject diagnosed as having a demential disease and differentiating the subject as a patient with a demential disease caused by normal pressure hydrocephalus if the measured concentration is significantly lower than those of control subjects.
(Deleted)
(Amended) A kit for differentiating a demential disease caused by normal pressure hydrocephalus comprising a monoclonal antibody specific to human lipocalin-type prostaglandin D synthase.
Dependencies are inferred from the claim text.