Novel phosphodiesterase and genes thereof
AssigneeTanabe Seiyaku Co., Ltd.
InventorsKenji Omori, Keizo Yuasa, Jun Kotera, Kotomi Oda, Hideo Michibata
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AssigneeTanabe Seiyaku Co., Ltd.
InventorsKenji Omori, Keizo Yuasa, Jun Kotera, Kotomi Oda, Hideo Michibata
Estimating the term…
The present invention is to provide a novel phosphodiesterase and a gene thereof, specifically, Type 11 phosphodiesterase (PDE11) and a gene thereof, more specifically, a phosphodiesterase selected from (A) a protein having an amino acid sequenced shown by SEQ.ID.NO: 2, SEQ.ID.NO: 4, SEQ.ID.NO: 6 or SEQ.ID.NO: 39, and (B) a protein having an amino acid sequence shown by SEQ.ID.NO: 2, SEQ.ID.NO: 4, SEQ.ID.NO: 6 or SEQ.ID.NO: 39 in which one or several amino acids are deleted, substituted or added, and having an activity of hydrolyzing a cyclic nucleotide, and a gene thereof, and a method of characterizing, identifying and selecting a phosphodiesterase inhibitor by using the same.
A type 11 phosphodiesterase.
A gene or a nucleic acid selected from the following (a) and (b):
A gene or a nucleic acid selected from the following (a) and (b):
Dependencies are inferred from the claim text.