Combinatorial synthesis
AssigneeEngelhard Corporation
InventorsAhmad Moini, Gerald Steven Koermer, Christopher R. Castellano
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Abstract
Methods are disclosed for providing a library of composite compositions on a support. The method involves depositing one or more components onto the support on either discrete spaced regions of the support or as a continuous concentration gradients on the surface of the support. The composite samples can be removed from the support by drilling out portions of the coated support so as to yield individual composite tablets containing the support with one or more component layers thereon. By using this method, a vast number of composites can be made and tested simultaneously.
Claims69
A method of producing a library of composite compositions on a substrate sheet comprising:
- forming a plurality of different composite compositions on said sheet, said composite compositions comprising one or more components deposited on said substrate sheet, and testing said composite compositions for properties, said method of producing said library devoid of any step which causes substantial reaction of any deposited component with another deposited component or said substrate sheet.
A method of making a library of a plurality of composite samples placed on a substrate sheet comprising:
- cutting the substrate sheet so as to provide said sheet with a plurality of cut shaped portions which are spaced from each other on the surface of the sheet, depositing at least one component on the surface of said sheet whereby the cut shaped portions of said sheet are covered by at least one of said deposited components, and removing said covered cut shaped portions of said sheet to form composite samples, said composite samples comprising said substrate containing at least one deposited component thereon in the form of said shaped portion, testing said composite samples for properties.
A ceramic sheet containing a plurality of cut shaped portions which are formed by perforating the surface of said ceramic sheet.
A method of producing a library of compositions on a substrate sheet comprising:
- forming a plurality of different compositions on said substrate sheet, said compositions formed by depositing at least two components on said substrate sheet and reacting said deposited components to form said compositions, removing said formed compositions along with said underlying substrate from said substrate sheet.
Dependencies are inferred from the claim text.