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US 2003/0190406 A1Published application
Implantable device having substances impregnated therein and a method of impregnating the same
AssigneeAdvanced Cardiovascular Systems, Inc.
InventorsSyed F. A. Hossainy, Jacqueline Ghio, Li Chen
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Abstract
The present invention provides a method of impregnating an implantable device, such as a vascular graft or a covering adapted to be disposed over a prosthesis. The substances may be impregnated within the implantable device as a passive coating or as a delivery matrix for a therapeutic substance. Also provided is an implantable device having such substances impregnated therein.
Claims67
A method of impregnating an implantable device, the method comprising the acts of:
- (a) providing a substrate having a body and interstices throughout said body;
- (b) applying a composition to said substrate such that said composition penetrates into said interstices of said body of said substrate, said composition comprising a first substance and a first fluid;
- and
- (c) removing essentially all of said first fluid from said composition within said body of said substrate, wherein said first substance remains within said body of said substrate.
1 more element
An implantable device comprising:
- (a) a substrate having a body and interstices within said body, said body having a first end, an opposing second end, and a hollow bore extending longitudinally through said body from said first end to said second end;
- (b) a first substance impregnated within said interstices of said body of said substrate;
- and
- (c) a prosthesis inserted at least partially within said hollow bore of said body of said substrate, said prosthesis having a plurality of depots formed therein.
1 more element
Dependencies are inferred from the claim text.