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AssigneeGinseng Science Inc.
InventorsDong-Hyun Kim, Eun-Ah Bae, Myung-Joo Han, Min-Kyung Choo, Eun-Kyung Park, Jeong-Hill Park
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The present invention relates to an extract of processed Panax genus plant, the preparation thereof and compositions containing the same having anticancer or anti-allergic activity. More particularly, the present invention relates to a processed ginseng product with enhanced pharmacological effects due to serial treatment i.e., acid-treatment or heat-treatment of a Panax genus plants and subsequent bio-converting treatment such as lactic fermenting and intestinal-bacterial fermenting process so as to make a ratio of ginsenoside (Rk2+Rh3+protopanaxadiol+20-dehydroprotopanaxadiol) to (Rg3+Rg5+Rk1) of above 0.1. The extract of processed Panax genus plant in the present invention has inhibitory effect for cancer or allergic diseases and it is useful in the prevention or treatment of cancer or allergic diseases.
A processed Panax genus plant or the extract thereof comprising a ratio of ginsenoside (Rk2+Rh3+protopanaxadiol+20-dehydroprotopanaxadiol) to (Rg3+Rg5+Rk1) of above 0.1.
A processed Panax genus plant or the extract thereof obtained by the steps essentially comprising acid or heat treating or their combination thereof the plant material belonged to Panax genus, and subsequent fermentation treating with lactic-acid bacteria or intestinal-bacteria.
A pharmaceutical compositions comprising saponin compounds selected from the group consisting of ginsenoside Rb1, Rb2, Re, Rg1, Rf, F1, F4, Rh1, Rg5, 20-ginsenoside Rg3, 20-ginsenoside Rh2, protopanaxadiol and the mixture thereof as an active ingredient in an amount effective to treat or prevent human or mammal in allergic diseases, together with a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.