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US 2003/0190365 A1Published application
Methods for wet granulating azithromycin
AssigneePfizer Inc.
InventorsMichael Fergione, Barbara A. Johnson
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AssigneePfizer Inc.
InventorsMichael Fergione, Barbara A. Johnson
Estimating the term…
The present invention relates to a method of forming non-dihydrate azithromycin granules, comprising mixing non-dihydrate azithromycin particles, with a granulating amount of a granulating liquid, and, optionally, with one or more excipients, to form wet granules which comprise non-dihydrate azithromycin and the granulating liquid. The granules are then dried to remove the granulating liquid. The invention further relates to a pharmaceutical composition comprising granules of a non-dihydrate azithromycin and at least one pharmaceutically acceptable excipient. The invention also relates to pharmaceutical formulations comprising granules of non-dihydrate azithromycin. The invention further relates to granules of dihydrate azithromycin wherein the granules comprises 98-100% dihydrate azithromycin and from about 0-2%, total weight, of one or more pharmaceutically acceptable excipients.
A method of forming non-dihydrate azithromycin granules, comprising:
A granule comprising non-dihydrate azithromycin and, optionally, one or more excipients wherein said granule is formed by a wet granulation process.
A granule comprising 98-100%, by weight, azithromycin and 0-2%, by weight, of one or more pharmaceutically acceptable excipients.
A pharmaceutical composition comprising granules of a non-dihydrate azithromycin, wherein said granules are formed by a wet granulation process, and at least one pharmaceutically acceptable excipient.
A pharmaceutical formulation, comprising:
A pharmaceutical formulation, comprising:
A pharmaceutical formulation, comprising:
Dependencies are inferred from the claim text.