Modified release minerals
OwnerMarc S. Hermelin, Michael Grimshawinventors
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Abstract
The present invention is directed to compositions and methods for the enhancement of iron uptake or the treatment of iron deficiency by enhancing the rate and extent of dissolution in a subject in need thereof. The composition contains at least two iron-providing materials in a single dosage form wherein at least one of the iron-providing materials contains a modified release mechanism, matrix, or coating. The iron-providing materials included within the composition have different rates of release. Following administration to the animal, the iron-providing materials are released in the gastrointestinal tract over a period of up to 24 hours.
Claims63
A composition for the enhancement of iron uptake or the treatment of iron deficiency by enhancing the rate and extent of iron dissolution in a subject in need thereof, which comprises:
- a combination of at least two iron-providing materials in a single dosage form;
- wherein at least one of the iron-providing materials has a modified release mechanism, matrix, or coating;
- wherein each of the iron-providing material has a different rate of release;
- and
- wherein the iron-providing materials are released in the gastrointestinal tract over a period of up to 24 hours.
A composition for the enhancement of iron uptake or the treatment of iron deficiency in a mammal in need thereof, which comprises:
- a combination of at least two iron-providing materials in a single dosage form;
- wherein at least one of the iron-providing materials has a modified release mechanism, matrix, or coating;
- wherein each of the iron-providing material has a different rate of release;
- and
- wherein the iron-providing materials are released in the gastrointestinal tract over a period of up to 24 hours.
A method for the enhancement of iron uptake or the treatment of iron deficiency in a subject in need thereof, which comprises:
- administering to said subject a therapeutically effective amount of at least two iron-providing materials combined in a single dosage form;
- wherein at least one of the iron-providing materials has a modified release mechanism, matrix, or coating;
- wherein each of the iron-providing material has a different rate of release;
- and
- wherein the iron-providing materials are released in the gastrointestinal tract over a period of up to 24 hours.
A method for the enhancement of iron uptake or the treatment of iron deficiency in a subject in need thereof, which comprises:
- administering to said subject a therapeutically effective amount of at least two iron-providing materials having different solubilities combined in a single dosage form;
- wherein the iron-providing materials naturally have different rates of release;
- and
- wherein the iron-providing materials are released in the gastrointestinal tract over a period of up to 24 hours.
Dependencies are inferred from the claim text.