Low water-soluble venlafaxine salts
AssigneeSynthon BV
InventorsMarinus J. M. Oosterbaan, Rolf Keltjens
Life of this patent
Estimating the term…
Abstract
Low water soluble salts of venlafaxine, especially venlafaxine maleate, are provided. Such salts can provide a variety of dosage forms including hydrogel-based extended release dosage forms.
Claims38
A venlafaxine maleate compound.
A pharmaceutical composition comprising a venlafaxine maleate compound and a pharmaceutically acceptable excipient.
A method for treating a venlafaxine-treatable disease or condition, which comprise administering to a patient in need thereof an effective amount of a venlafaxine maleate compound.
A process for making venlafaxine maleate comprising contacting a venlafaxine substrate and maleate substrate in a suitable solvent, optionally followed by preparation of venlafaxine maleate from the solvent.
A low water-soluble venlafaxine salt other than venlafaxine besylate.
A pharmaceutical composition comprising a low water-soluble venlafaxine salt compound, other than venlafaxine besylate, and a hydrophilic matrix material.
Dependencies are inferred from the claim text.