Composite sponge wound dressing made of beta-chitin and chitosan and method for producing the same
AssigneeChina Textile Institute
InventorsJui-Sheng Lee, Chun-Yuan Hsu, Wei-Hsin Lin
Life of this patent
Estimating the term…
Abstract
The present invention relates to a composite sponge wound dressing and method for producing the same. Chitosan and β-Chitin is mixed in a specific ratio for forming the sponge for wound repairing. Particularly, when said ratio is between 0.1-1, the composite sponge wound dressing has a better absorption and tensile strength.
Claims17
1 A method for producing composite sponge wound dressing made of β-Chitin and Chitosan, which comprises the steps of:
- a.) providing a β-Chitin and a Chitosan;
- b.) putting said β-Chitin in deionized water (D.I. Water);
- c.) blending said β-Chitin in high speed for forming a hydrogel β-Chitin;
- d.) solving said Chitosan by an acid liquid;
- e.) filtering said Chitosan;
- f.) mixing said hydrogel β-Chitin from step c and said Chitosan from step e;
- g.) forming a sponge by freeze-drying;
- h.) immersing said sponge in an alkaline liquid for forming salt by neutralization;
- i.) cleaning and removing said salt with water until said sponge becoming neutral;
- j.) cleaning said sponge with D.I. Water repeatedly;
- and
- k.) producing a composite sponge wound dressing made of β-Chitin and Chitosan by vacuum drying.
2 The method of claim 1, wherein the sequence of the steps b, c and steps d, e is synchronizing.
3 The method of claim 1, the step f mixing said Chitosan and said hydrogel β-Chitin further accords with a specific ratio of Chitosan and β-Chitosan, wherein said ratio is between 0.1-1.
4 The method of claim 3, wherein said ratio is between 0.125-0.5.
5 The method of claim 1, wherein said β-Chitin is short staple β-Chitin.
6 The method of claim 1, wherein said Chitosan is membrane Chitosan.
7 The method of claim 1, wherein said acid liquid is 2% acetic acid.
8 The method of claim 1, wherein said alkaline liquid is 5% sodium hydroxide (NaOH) liquor.
9 The method of claim 1, after forming said composite sponge wound dressing made of β-Chitin and Chitosan, further comprises the step of covering said composite sponge wound dressing with a protection dressing for wound repairing.
10 The method of claim 9, wherein said protection dressing is selected from a group of PU film, bandage, non-woven, fabric, paper, and tape.
11 A composite sponge wound dressing made of β-Chitin and Chitosan, which comprises a specific ratio of Chitosan and β-Chitin for wound repairing.
12 The composite sponge wound dressing of claim 11, wherein said ratio is between 0.1-1.
13 The composite sponge wound dressing of claim 11, wherein said ratio is between 0.125-0.5.
14 The composite sponge wound dressing of claim 11, wherein said β-Chitin is short staple β-Chitin.
15 The composite sponge wound dressing of claim 11, wherein said Chitosan is membrane Chitosan.
16 The composite sponge wound dressing of claim 11 further comprises a protection dressing, wherein said protection dressing is covering on said composite sponge wound dressing for wound repairing.
17 The composite sponge wound dressing of claim 16, wherein said protection dressing is selected from a group of PU film, bandage, non-woven, fabric, paper, and tape.