Plaster preparation

#The invention relates to plaster preparations that can be used in the case of irritations (formications, burns and itches) resulting from contact with stinging nettles or similar irritations.

#Skin irritations such as those caused by mosquito bites or contact with stinging nettles or jellyfish are invariably found to be unpleasant and troublesome. The skin irritations described in the present patent specification are all reactions involving slight reddening, weals, blisters but not pathological states such as high-degree sensitisation resulting in anaphylactic shock or the secondary formation of granulomas in the clinical picture of prurigo. The skin irritations referred to here, which are to be treated with the product according to the invention, chiefly occur after time spent outdoors, for example as occurring during children's play in woods, fields or at the edge of water but also during summer holidays or in hot resorts, or while playing sports although they may also be acquired otherwise. The skin irritations described above should be interpreted as follows in medical terms.

#According to textbooks (e.g., Jung, Dermatologie, 1991), minor irritation at the nociceptors of the skin produces itching while more serious irritation causes pain. Itching may also be a reaction to chemical, mechanical or thermal stimuli. This results in weals and/or urticaria through the effect of chemical substances such as from insect bites (e.g., histamine from mosquito bites, apamin from bee stings, stinging nettles etc.), allergic immune reactions to chemical substances; the effect of pressure and/or rubbing (e.g. with a paper clip or a wooden spatula, the rubbing of fine hairs), from heat (sport, heated pads) and from light (sunburn). An itchy weal and/or urticaria shows all the signs of irritation such as reddening, swelling, heat, “pain” or itching and is due to the cutaneous release of histamine. Itching has not been fully explained in medical terms and always involves a subjective, in some cases psychological, element.

#To produce 1800 cm2 of a yellow plaster laminate according to the invention on a laboratory scale 1.385 g menthol, 1.440 g thesit and 4.5 g tincture of plantain 4%, 43.927 g Durotak® 87-2852 and 2.3 ml ethanol 96% are mixed and added, followed by 323.5 mg beta-carotene, and then homogenised by stirring. The paste is spread with a scraper on a siliconised polyester foil in a wet layer of 400 μm to produce a surface weight of 100 g/m2 after drying. After laminating with Cotran # 9720 a bright yellow plaster 4.0 cm2 in size contains 1.5 mg menthol.

#To produce 1800 cm2 of a red plaster laminate according to the invention on a laboratory scale 1.385 g menthol, 1.440 g thesit and 4.5 g tincture of plantain 4%, 43.927 g Durotak® 87-2852 and 2.3 ml ethanol 96% are mixed and added, followed by 212.5 mg iron (III) oxide, and then homogenised by stirring. The paste is spread with a scraper on a siliconised polyester foil in a wet layer of 400 μm to produce a surface weight of 100 g/m2 after drying. After laminating with Cotran # 9720 a bright red plaster 4.0 cm2 in size contains 1.5 mg menthol.

#The above examples can of course also be produced without dyes to permit usage by adults, who can then directly see the soothing therapeutic effect of the plaster on the skin irritation through the transparent plaster, and to also offer relief for skin irritations in the facial area as discretely and inconspicuously as possible in cosmetically acceptable terms.