Conjugated drug-polymer coated stent
AssigneePoly-Med, Inc.
InventorsShalaby W. Shalaby, Todd Campbell
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Abstract
One aspect of the invention is a system for treating vascular conditions, including a catheter, a stent coupled to the catheter, and a polymeric coating on the stent comprising at least one conjugated drug. Each conjugated drug includes a control agent and a bioactive agent, where the control agent controls the elution rate of the bioactive agent.
Claims62
A system for treating a vascular condition, comprising:
- a catheter;
- a stent coupled to the catheter;
- and
- a polymeric coating on the stent comprising at least one conjugated drug, wherein each conjugated drug includes a control agent and a bioactive agent, wherein the control agent controls an elution rate of the bioactive agent.
A drug-polymer coated stent, comprising:
- a cardiovascular stent including a stent framework;
- and
- a polymeric coating on the stent framework, wherein the polymeric coating comprises a biocompatible polymer with an interdispersed conjugated drug, wherein the elution rate of the interdispersed conjugated drug is predetermined.
A drug-polymer coated stent, comprising:
- a cardiovascular stent including a stent framework;
- and
- a polymeric coating on the stent framework, wherein the polymeric coating comprises a conjugated drug, wherein the elution rate of the conjugated drug is predetermined.
A method of manufacturing a drug-polymer coated stent, comprising:
- providing a stent framework;
- forming a conjugated drug, wherein the conjugated drug comprises a bioactive agent and a control agent;
- and
- coating the stent framework with the conjugated drug.
A method for treating vascular conditions, comprising:
- inserting a stent within a vessel in a body;
- separating at least a portion of a polymeric coating on the stent into a bioactive agent and a control agent;
- and
- eluting the bioactive agent.
A system for treating a vascular condition, comprising:
- means for inserting a stent within a vessel in a body;
- means for allowing separation of at least a portion of a polymeric coating on the stent into a bioactive agent and a control agent;
- and
- means for eluting the bioactive agent.
Dependencies are inferred from the claim text.