Diagnostic tests for anti-endotoxin core antibodies

A kit for use in determining whether a patient could benefit from treatment with an anti-endotoxin compound, said kit comprising (i) a solid substrate comprising an endotoxin from a gram-negative bacterium, and (ii) instructions stating what level of anti-endotoxin core antibodies detected by use of the kit indicates that the patient could benefit from treatment with an anti-endotoxin compound.

A method of treating a patient that has or is at risk of developing a condition that is treatable by the use of an anti-endotoxin compound, said method comprising the steps of (i) determining the level of anti-endotoxin core antibodies in a sample from the patient, and, if the levels of anti-endotoxin core antibodies in the sample are inadequate, (ii) administering an antiendotoxin compound to the patient.