Treatment of Kaposi's sarcoma with IL-12
AssigneeWyeth and National Institutes of Health
InventorsRobert Yarchoan, James M. Pluda, Kathleen Wyvill, Jill Lietzau, Gene M. Shearer, Ellen Feigal, Giovanna Tosato, Richard Little, Matthew L. Sherman
Life of this patent
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Abstract
Methods are provided for using IL-12 to treat Kaposi's sarcoma (KS), particularly AIDS-associated KS.
Claims14
A method for treating Kaposi's sarcoma in a mammalian subject, said method comprising administering to said subject a therapeutically effective amount of IL-12 or a biologically active fragment or subunit thereof.
A method for inhibiting angiogenesis in a lesion associated with Kaposi's sarcoma in a mammalian subject, said method comprising administering to said subject a therapeutically effective amount of IL-12 or a biologically active fragment or subunit thereof.
The method of claim 9 wherein said subject has AIDS.
Dependencies are inferred from the claim text.