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AssigneeKawamura Institute of Chemical Research
InventorsTakanori Anazawa, Atsushi Teramae
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There is provided a micro chemical device with a valve function for which the pressure resistance is high and the channel cross-sectional area does not depend on the fluid pressure, and which furthermore enables the suppression of the adsorption of biological matter and yet is easy to produce, as well as a flow regulation method using such a device. This has a valve function, in which a member (B) is bonded to a member (A) with a groove in the surface thereof, via the surface of the member (A) in which the groove is formed, a capillary type channel of width from 1 to 1000 μm and height from 1 to 1000 μm is formed by the groove of the member (A) and the member (B) at the bonding surface between the member (A) and the member (B), a cavity section is formed partway along the channel and the width of this cavity section is from 0.5 to 100 fold the width of the capillary type channel and the ratio of maximum height/maximum width for the cavity section is no more than 1, and either one of the member (A) and the member (B) is formed from a soft material with a tensile modulus of elasticity within a range from 0.1 MPa to 700 MPa, at least within the portion which corresponds with the position of the cavity section, wherein by selectively compressing the cavity section from the external surface of the member (A) and/or the member (B), the volume of the cavity section can be reduced in a reversible manner.
A micro chemical device with a valve function, in which a member (B) is bonded to a member (A) with a groove in the surface thereof, via the surface of the member (A) in which the groove is formed, a capillary type channel of width from 1 to 1000 μm and height from 1 to 1000 μm is formed by the groove of the member (A) and the member (B) at the bonding surface between the member (A) and the member (B), a cavity section is formed partway along the channel and the width of this cavity section is from 0.5 to 100 fold the width of the capillary type channel and the ratio of maximum height/maximum width for the cavity section is no more than 1, and either one of the member (A) and the member (B) is formed from a soft material with a tensile modulus of elasticity within a range from 0.1 MPa to 700 MPa, at least within the portion which corresponds with the position of the cavity section, wherein by selectively compressing the cavity section from the external surface of the member (A) and/or the member (B), the volume of the cavity section can be reduced in a reversible manner.
9 A micro chemical device according to any one of claim 5 through claim 8, wherein the convex structure is formed from a hard material with a tensile modulus of elasticity of at least 700 Mpa.
A micro chemical device with a valve function, in which by bonding a member (B) and a member (C) together with a layer type member (D) comprising a lacking section for forming a channel disposed therebetween, a capillary type channel of width from 1 to 1000 μm and height from 1 to 1000 μm is formed between the member (B) and the member (C) by the lacking section of the material of the member (D), and a cavity section is formed partway along the channel and the width of this cavity section is from 0.5 to 100 fold the width of the capillary type channel and the ratio of maximum height/maximum width for the cavity section is no more than 1, and any one of the members (B), (C) and (D) is formed from a soft material with a tensile modulus of elasticity within a range from 0.1 MPa to 700 MPa, at least within the portion which corresponds with the cavity section (or in the case of the member (D), the portion surrounding the cavity section), and any one of the members (B), (C) and (D) is formed from a medium hard material or a hard material with a tensile modulus of elasticity of at least 700 MPa, wherein by compressing the cavity section from the external surface of the member (B), the volume of the cavity section can be reduced in a reversible manner.
13 A micro chemical device according to claim 12, wherein the member (B) is formed from a soft material with a tensile modulus of elasticity within a range from 0.1 MPa to 700 MPa, at least within the portion which corresponds with the cavity section, and the minimum thickness of the portion which corresponds with the cavity section is within a range from 10 to 3000 μm.
A micro chemical device with a valve function, in which a member (B) is bonded to a member (A) with a groove in the surface thereof, via the surface of the member (A) in which the groove is formed, a capillary type channel of width from 1 to 1000 μm and height from 1 to 1000 μm is formed by the groove of the member (A) and the member (B) at the bonding surface between the member (A) and the member (B), a cavity section is formed partway along the channel and the width of this cavity section is from 0.5 to 100 fold the width of the capillary type channel and the ratio of maximum height/maximum width for the cavity section is no more than 1, and both the member (A) and the member (B) are formed from a soft material with a tensile modulus of elasticity within a range from 0.1 MPa to 700 MPa, at least within the portion which corresponds with the cavity section, and a convex structure is provided on the surface of the member (A) and/or the member (B), in a position corresponding with the cavity section, wherein by compressing the cavity section from the external surface of the member on which the convex structure is provided, the volume of the cavity section can be reduced in a reversible manner.
A micro chemical device with a valve function, in which a member (B) is bonded to a member (A) with a groove in the surface thereof, via the surface of the member (A) in which the groove is formed, a capillary type channel of width from 1 to 1000 μm and height from 1 to 1000 μm is formed by the groove of the member (A) and the member (B) at the bonding surface between the member (A) and the member (B), a cavity section is formed partway along the channel and the width of this cavity section is from 0.5 to 100 fold the width of the capillary type channel and the ratio of maximum height/maximum width for the cavity section is no more than 1, and both the member (A) and the member (B) are formed from a soft material with a tensile modulus of elasticity within a range from 0.1 MPa to 700 MPa, at least within the portion which corresponds with the cavity section, and a member (H) with a convex structure is laminated onto the member (A) and/or the member (B), or alternatively is laminated onto a sheet type member (E) with a thickness from 0.5 to 500 μm, which is formed from a medium hard material with a tensile modulus of elasticity within a range from 700 MPa to 10 GPa provided on the outside of the member (A) and/or the member (B), and the convex structure is fixed in a position corresponding with the cavity section, wherein by compressing the cavity section from the surface of the member with the convex structure, the volume of the cavity section can be reduced in a reversible manner.
A micro chemical device with a valve function, in which by bonding a member (B) and a member (C) together with a layer type member (D) comprising a lacking section for forming a channel disposed therebetween, a capillary type channel of width from 1 to 1000 μm and height from 1 to 1000 μm is formed between the member (B) and the member (C) by the lacking section of the material of the member (D), and a cavity section is formed partway along the channel and the width of this cavity section is from 0.5 to 100 fold the width of the capillary type channel and the ratio of maximum height/maximum width for the cavity section is no more than 1, and each of the members (B), (C) and (D) is formed from a soft material with a tensile modulus of elasticity within a range from 0.1 MPa to 700 MPa, at least within the portion which corresponds with the cavity section (or in the case of the member (D), the portion surrounding the cavity section), and a convex structure is provided on the surface of the member (B) in a position corresponding with the cavity section, wherein by compressing the cavity section from the surface of the member (B), the volume of the cavity section can be reduced in a reversible manner.
A micro chemical device with a valve function, in which by bonding a member (B) and a member (C) together with a layer type member (D) comprising a lacking section for forming a channel disposed therebetween, a capillary type channel of width from 1 to 1000 μm and height from 1 to 1000 μm is formed between the member (B) and the member (C) by the lacking section of the material of the member (D), and a cavity section is formed partway along the channel and the width of this cavity section is from 0.5 to 100 fold the width of the capillary type channel and the ratio of maximum height/maximum width for the cavity section is no more than 1, and each of the members (B), (C) and (D) is formed from a soft material with a tensile modulus of elasticity within a range from 0.1 MPa to 700 MPa, at least within the portion which corresponds with the cavity section (or in the case of the member (D), the portion surrounding the cavity section), and a member (H) with a convex structure is laminated onto the member (B), or alternatively is laminated onto a sheet type member (E) with a thickness from 0.5 to 500 μm, which is formed from a medium hard material with a tensile modulus of elasticity within a range from 700 MPa to 10 GPa provided on the outside of the member (B), and the convex structure is fixed in a position corresponding with the cavity section, wherein by compressing the cavity section from the surface of the member (B), the volume of the cavity section can be reduced in a reversible manner.
A micro chemical device flow regulation method, wherein by selectively compressing a cavity section of a micro chemical device according to any one of (1) through (27) above from externally, the volume of the cavity section within the micro chemical device can be reduced in a reversible manner, and the flow rate of a fluid passing through the cavity section can be regulated.
Dependencies are inferred from the claim text.