Loading patent…
OwnerJose Rivera Torres, Francisco Rodriguez +4inventors
InventorsJose Rivera Torres, Francisco Rodriguez, Maria D. Fernandez, Juan Antonio Garcia Alvarez, Juan Plana-Duran, Mercedes Mourino
Estimating the term…
The VP60 structural antigen or a fragment therof of rabbit hemorrhagic disease virus (RHDV) can be obtained in plants using a viral vector based on the plum pox virus (PPV), which includes a promoter, a recombinant DNA sequence including a cDNA to the genome of the PPV virus, full-length, and a DNA sequence which codes for the RHDV VP60 protein or a fragment thereof inserted between the nucleotide sequences coding the Nib and CP proteins of the PPV virus, and a cloning vehicle. The antigen obtained is capable of inducing protection in rabbits against a lethal challenge of RHDV, and can be used as a recombinant subunit vaccine against rabbit hemorrhagic disease virus.
An expression vector of the VP60 antigen of rabbit hemorrhagic disease virus (RHDV) or a fragment thereof, based on the plum pox virus (PPV), which comprises:
Dependencies are inferred from the claim text.