Polymeric anion exchanger resins and their utilization in chromatographic methods

An anion-exchange resin that is obtainable through the polymerisation of at least one acrylic acid derivative together with at least one cross-linking agent, in which the acrylic acid derivative corresponds to the general formula (I):

• 6
• And R1 represents hydrogen, a methyl- or ethyl group, R2 and R3, that are unconnected to one another, represent hydrogen, a C1-C3-alkyl group or a hydroxyl-substituted C1-C3-alkyl group, X represents an —(NH)— group or an —(NR4)— group, and R4 represents a C1-C3-alkyl group, and Y represents a (CH2)m—(CH2O)n— group, in which m and n are independent of one another and denote the whole numbers 0, 1, 2, 3, 4, 5 or 6, in which m+n is >0 and one or both of the hydrogens of the Y group can be replaced by a C1-C3-alkyl group or by an acrylic acid derivative of the general formula (II):
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• and in which R*1 represents hydrogen, a methyl- or ethyl-group, and X represents oxygen or an —(NH)— group,
• in which the cross-linking agent corresponds to the general formula (III):
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• and R5 and R6 are independent of one another and represent hydrogen, a methyl- or ethyl group, and Q1 and Q2 represent oxygen, and Z represents a {[(CH2)o]O}p—(CH2)q group, in which o, p and q are independent of one another and denote whole numbers 0, 1, 2 or 3 and o+p+q is >0, and in which at least one hydrogen atom in the Z group can be replaced by a C1-C3-alkyl group or an —[(CH2)r—O]s—(CH2)t—NR8R9 group, that are independent of one another, in which r, s and t, independently of one another, represent the whole number 0, 1, 2, 3, 4, 5 or 6, and r+s+t is >0, and R8 and R9 are independent of one another and represent hydrogen, a C1-C3-alkyl group or a hydroxyl-substituted C1-C3-alkyl group.