2-pyridylmethylamine derivatives useful as fungicides
AssigneeAventis CropScience UK Limited
InventorsBrian Anthony Moloney, David Hardy, Elizabeth Anne Saville-Stones
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Abstract
Compounds of formula (I) and salts thereof as phytopathogenic fungicides wherein A1 is substituted 2-pyridyl; A2 is optionally substituted phenyl; L is —(C═O)—, —SO2— or —(C═S)—; R1 is hydrogen, optionally substituted alkyl or acyl; and R2 is hydrogen or optionally substituted alkyl are useful phytopathogenic fungicides.
Claims6
1 The use of compounds of formula I and salts thereof as phytopathogenic fungicides
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- wherein
- A1 is substituted 2-pyridyl;
- A2 is optionally substituted phenyl;
- L is —(C═O)—, —SO2— or —(C═S)—;
- R1 is hydrogen, optionally substituted alkyl or acyl;
- and
- R2 is hydrogen or optionally substituted alkyl.
2 A compound of formula I as described in claim 1 and salts thereof, in which A1 is a 2-pyridyl group having substituents at the 3 and/or 5 position and no other position, R1 and R2 are hydrogen and A2 and L are as defined in claim 1.
3 A pesticidal composition comprising compounds as defined in claim 1 or claimed in claim 2 in admixture with an agriculturally acceptable diluent or carrier.
A method of combating phytopathogenic fungi, at a locus infested or liable to be infested therewith, which comprises applying to the locus a compound of formula I as defined in claim 1 or claimed in claim 2.
5 A process for preparing intermediate compounds of formula IIa
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- comprising the steps of:
- a) reacting under basic conditions, compounds of formula IV with compounds of formula V to give intermediates of formula VI,
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- b) converting intermediates of formula VI to intermediates of formula VII,
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- c) converting intermediates of formula VII to compounds of formula IIa,
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- wherein
- Ra and Rb, which may be the same or different, are alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, heterocyclyl or phenyl, each of which may be substituted (preferably optionally substituted phenyl);
- E1 is both an electron withdrawing group and a group which may be replaced by hydrogen using methodology known to the skilled chemist in accordance with step c) (preferably a carboxy group or a carboxy ester group);
- X1 is a leaving group;
- and
- A1 and R1 are as defined in claim 1.
5 As intermediates, compounds of formula IIb and salts thereof,
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- wherein A1 is defined in claim 1 and R1 is optionally substituted alkyl.
Dependencies are inferred from the claim text.