Therapeutic method of delivering a medicament to avoid irritating effects on membranes of user
OwnerJay L. Caplaninventor
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Abstract
A composition for administration to the nasal mucosa or as an oral inhalant comprises a molecule which is the reaction product of nicotine with two molecules of a sweetener such as acesulfamic acid. The resultant molecule of nicotine diacesulfamate in a pharmaceutically acceptable solvent offers an improved side effect profile as regards irritation and unpleasant taste for the subject using the composition.
Claims34
A method of providing an improved means of delivering a therapeutically effective dosage sufficient to provide the desired therapeutic result and to ameliorate any adverse effects on the nasal passages, throat, nose, lungs, eyes, and other mucous membranes of the user resulting from delivery therein by nasal or oral means to an individual, comprising applying the reaction product of a compound selected from the group consisting of a pharmaceutical, a synthetic non-alkaloidal medical organic base, or a medicament and a sweetener in a solvent to said individual.
The method defined in claim 8 wherein said sweetener is diacesulfamate.
The method defined in claim 9 wherein said solvent is selected from the group consisting of water, ethanol, isopropyl alcohol, other alcohols, propylene glycol, polyethylene glycol, vegetable oils, n-ethylene glycol(s), halogenated organic solvents, or povidone.
Dependencies are inferred from the claim text.