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OwnerChristopher Franklin Bigge, Alexander James Bridges +8inventors
InventorsChristopher Franklin Bigge, Alexander James Bridges, Agustin Casimiro-Garcia, Stephen Alan Fakhoury, Helen Tsenwhei Lee, Jessica Reed, Robert Schaum, Kevin Matthew Schlosser, Karen Sexton, Hairong Zhou
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The present invention provides compounds of Formula (I): 1 wherein A, X, Q, Y, B, D, Z, and E have any of the values defined in the specification, and pharmaceutically acceptable salt thereof, that are useful as antidiabetic agents. Also disclosed are pharmaceutical compositions comprising one or more compounds of Formula I, processes for preparing compounds of Formula I, and intermediates useful for preparing compounds of Formula I.
A compound of formula (I)
The compound of claim l, wherein E is CO2H, CO2Me, or CO2tBu.
A compound of formula (II)
A compound of formula (III):
The compound which is:
A compound which is:
A compound which is:
The invention also provides a compound which is:
The invention also provides a compound which is:
A process for preparing a compound of formula IV
A process for preparing a compound of formula II,
A process for preparing a compound of formula (III):
Dependencies are inferred from the claim text.