Pharmaceutical composition containing at least a polymer combined with or conjugated to at least a phenylalkylcarboxylic acid salt, conjugate polymers and uses thereof

A pharmaceutical composition, characterized in that it comprises, as active principle, at least one composition chosen from the group consisting of:

• a) a conjugate of a polymer comprising at least one free hydroxyl function and of at least one phenylalkylcarboxylic acid derivative of formula (I) below:
• R2—(CH2)n—COOR1 (I)
• in which:
• R1 represents a hydrogen atom, a halogen atom, an atom of a monovalent alkali metal such as sodium or potassium, or a group —CO(CH2)mR3,
• R2 and R3 represent an unsubstituted phenyl radical,
• n and m, which are identical, are integers of between 1 and 3 inclusive;
• said conjugate corresponding to formula (III) below:
• (Polymer)-(OOC—(CH2)n—R2)d (III)
• in which the polymer comprises at least one free hydroxyl function, n is an integer of between 1 and 3 inclusive, R2 represents an unsubstituted phenyl radical and d, which is the index of substitution (ds) of derivative of formula (I), is ≧0.05 and ≦1.5, and preferably >0.15;
• b) a combination of at least one polymer having a molecular mass of greater than or equal to 5000 Da and comprising at least one free hydroxyl function, and of at least one phenylalkylcarboxylic acid salt of formula (I′) below:
• R′2—(CH2)n′—COOR′1 (I′)
• in which:
• R′1 is an atom of a monovalent alkali metal such as sodium or potassium,
• R′2 represents an unsubstituted phenyl radical,
• n′ is an integer of between 1 and 3 inclusive;
• c) and mixtures thereof, and optionally one or more other additional active principles, and possibly in the presence or not of a pharmaceutically acceptable vehicle and/or of a physiologically acceptable carrier.