Foot and mouth disease virus vaccine
AssigneeThe United States of America as represented by the Secretary of Agriculture
InventorsMarvin J. Grubman, Jarasvech Chinsangaram, Marla Koster, Mauro P. Moraes
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Abstract
Early protection of susceptible animals against foot and mouth disease (FMD) may be achieved by inoculating the animals with a vaccine comprising an interferon DNA sequence. One day after inoculation, animals have been found protected from challenge with virulent foot and mouth disease virus. Co-administration with an effective foot and mouth disease virus vaccine provides protection prior to the development of specific immunity, a feature especially desireable during a FMD outbreak.
Claims23
A construct comprising a DNA sequence capable of expressing interferon in animals susceptible to foot and mouth disease, wherein said interferon is expressed upon administration to said animals.
Dependencies are inferred from the claim text.