Antisense modulation of RECQL expression
AssigneeIsis Pharmaceuticals, Inc.
InventorsDonna T. Ward, Andrew T. Watt
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Abstract
Antisense compounds, compositions and methods are provided for modulating the expression of RECQL. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding RECQL. Methods of using these compounds for modulation of RECQL expression and for treatment of diseases associated with expression of RECQL are provided.
Claims20
A compound 8 to 50 nucleobases in length targeted to a nucleic acid molecule encoding RECQL, wherein said compound specifically hybridizes with and inhibits the expression of RECQL.
A compound 8 to 50 nucleobases in length which specifically hybridizes with at least an 8-nucleobase portion of an active site on a nucleic acid molecule encoding RECQL.
Dependencies are inferred from the claim text.