Treatment of bone disorders with skeletal anabolic drugs
AssigneeOsteotrophin, LLC
InventorAndrew F. Stewart
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Abstract
Disclosed herein are methods for the prevention and treatment of a variety of mammalian conditions manifested by loss of bone mass, including osteoporosis. The present invention provides methods of using PTHrP, or analogs thereof, for the treatment of metabolic bone disorders that are both effective and have an increased safety.
Claims11
A method of increasing bone mass in a human patient in need thereof, said method comprising administering intermittently to said patient PTHrP-(1-36) for a period of at least 3 months, wherein the bone mass density of said patient increases at a rate of at least 1% per month.
A method of increasing bone mass in a human patient in need thereof, said method comprising administering intermittently to said patient PTHrP-(1-36) at a dose of 400 μg/day for a period of three months, wherein the bone mass density of said patient increases at least 3%.
Dependencies are inferred from the claim text.