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OwnerNaoki Tohdoh, Masashi Murata +1inventors
InventorsNaoki Tohdoh, Masashi Murata, Takashi Enjoji
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To provide a prophylactic or therapeutic agent for chronic hepatitis, capable of inhibiting the binding of hepatitis virus and a target cell, thereby preventing or treating chronic hepatitis; and a fusion interferon capable of still more improving a viral clearance ratio at the termination of interferon administration. A prophylactic or therapeutic agent for chronic hepatitis, comprising an oligopeptide having the following characteristics: (A) having a binding affinity to a viral antigen protein; (B) inhibiting binding of virus to a receptor protein on a target cell for said virus; and (C) having homologies with said receptor protein at the amino acid sequence level; a fusion interferon containing an amino acid sequence of the above-mentioned oligopeptide; and method for treating chronic hepatitis in combination with the use of interferon, characterized by using the oligopeptide or a part thereof in combination with interferon.
(amended) A prophylactic or therapeutic agent for chronic type-C hepatitis, comprising an oligopeptide having at least one kind of an amino acid sequence selected from the group consisting of SEQ ID NOs:
(amended) A prophylactic or therapeutic agent for chronic type-C hepatitis, comprising a nucleic acid having at least one kind of a nucleotide sequence selected from the group consisting of SEQ ID NOs:
(amended) A prophylactic or therapeutic agent for chronic type-C hepatitis, comprising a nucleic acid having at least one kind of a nucleotide sequence selected from the group consisting of SEQ ID NOs:
(amended) A prophylactic or therapeutic agent for chronic type-B hepatitis, comprising a compound having the following characteristics:
(amended) A prophylactic or therapeutic agent for chronic type-B hepatitis, comprising a nucleic acid having a nucleotide sequence of SEQ ID NO:
(amended) A fusion interferon containing an amino acid sequence of an oligopeptide having the following characteristics:
(amended) A fusion interferon containing at least one kind of an amino acid sequence selected from the group consisting of SEQ ID NOs:
(amended) A fusion interferon containing at least one kind of an amino acid sequence selected from the group consisting of SEQ ID NOs:
(amended) A fusion interferon containing an amino acid sequence of SEQ ID NO:
(amended) A method for treating chronic hepatitis in combination with the use of interferon, characterized by using an oligopeptide in combination with interferon, wherein said oligopeptide has the following characteristics:
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Dependencies are inferred from the claim text.