Process for preparing nonracemic chiral alcohols
AssigneeDsm N.V.
InventorsCharles E. Tucker, Qiongzhong Jiang
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Abstract
The present invention provides a catalyst system and a process for the preparation of a nonracemic chiral alcohol by hydrogenation of a ketone using the catalyst system, wherein the catalyst system comprises ruthenium, a nonracemic chiral diphosphine ligand, an amino-thioether ligand, and a base.
Claims21
A catalyst system useful for the hydrogenation of a ketone to a nonracemic chiral alcohol comprising ruthenium, a nonracemic chiral diphosphine ligand, an amino-thioether ligand, and a base.
A process for the preparation of a nonracemic chiral alcohol comprising hydrogenating a ketone in the presence of a catalyst system, wherein the catalyst system comprises ruthenium, a nonracemic chiral diphosphine ligand, an amino-thioether ligand, and a base.
Dependencies are inferred from the claim text.