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AssigneeGenentech, Inc.
InventorsDavid Botstein, Luc Desnoyers, Napoleone Ferrara, Sherman Fong, Wei-Qiang Gao, Audrey Goddard, Austin L. Gurney, James Pan, Margaret Ann Roy, Timothy A. Stewart, Daniel Tumas, Colin K. Watanabe, William I. Wood
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The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Isolated nucleic acid having at least 80% nucleic acid sequence identity to a nucleotide sequence that encodes an amino acid sequence selected from the group consisting of the amino acid sequence shown in FIG. 2 (SEQ ID NO:2), FIG. 4 (SEQ ID NO:7), FIG. 6 (SEQ ID NO:9), FIG. 8 (SEQ ID NO:11), FIG. 10 (SEQ ID NO:16), FIG. 12 (SEQ ID NO:18), FIG. 14 (SEQ ID NO:20), FIG. 16 (SEQ ID NO:22), and FIG. 18 (SEQ ID NO:24).
Isolated nucleic acid having at least 80% nucleic acid sequence identity to a nucleotide sequence selected from the group consisting of the nucleotide sequence shown in FIG. 1 (SEQ ID NO:1), FIG. 3 (SEQ ID NO:6), FIG. 5 (SEQ ID NO:8), FIG. 7 (SEQ ID NO:10), FIG. 9 (SEQ ID NO:15), FIG. 11 (SEQ ID NO:17), FIG. 13 (SEQ ID NO:19), FIG. 15 (SEQ ID NO:21) and FIG. 17 (SEQ ID NO:23).
Isolated nucleic acid having at least 80% nucleic acid sequence identity to a nucleotide sequence selected from the group consisting of the full-length coding sequence of the nucleotide sequence shown in FIG. 1 (SEQ ID NO:1), FIG. 3 (SEQ ID NO:6), FIG. 5 (SEQ ID NO:8), FIG. 7 (SEQ ID NO:10), FIG. 9 (SEQ ID NO:15), FIG. 11 (SEQ ID NO:17), FIG. 13 (SEQ ID NO:19), FIG. 15 (SEQ ID NO:21) and FIG. 17 (SEQ ID NO:23).
Isolated nucleic acid having at least 80% nucleic acid sequence identity to the full-length coding sequence of the DNA deposited under ATCC accession number 203538, 203661, 203583, 203657, 203576, 203573, 203553, 203651 and 203537.
An isolated polypeptide having at least 80% amino acid sequence identity to an amino acid sequence selected from the group consisting of the amino acid sequence shown in FIG. 2 (SEQ ID NO:2), FIG. 4 (SEQ ID NO:7), FIG. 6 (SEQ ID NO:9), FIG. 8 (SEQ ID NO:11), FIG. 10 (SEQ ID NO:16), FIG. 12 (SEQ ID NO:18), FIG. 14 (SEQ ID NO:20), FIG. 16 (SEQ ID NO:22), and FIG. 18 (SEQ ID NO:24).
An isolated polypeptide scoring at least 80% positives when compared to an amino acid sequence selected from the group consisting of the amino acid sequence shown in FIG. 2 (SEQ ID NO:2), FIG. 4 (SEQ ID NO:7), FIG. 6 (SEQ ID NO:9), FIG. 8 (SEQ ID NO:11), FIG. 10 (SEQ ID NO:16), FIG. 12 (SEQ ID NO:18), FIG. 14 (SEQ ID NO:20), FIG. 16 (SEQ ID N0:22), and FIG. 18 (SEQ ID NO:24).
An isolated polypeptide having at least 80% amino acid sequence identity to an amino acid sequence encoded by the full-length coding sequence of the DNA deposited under ATCC accession number 203538, 203661, 203583, 203657, 203576, 203573, 203553, 203651 and 203537.
Isolated nucleic acid having at least 80% nucleic acid sequence identity to:
An isolated polypeptide having at least 80% amino acid sequence identity to:
Dependencies are inferred from the claim text.