Enzyme variants having one or more D-amino acid substitutions
OwnerDavid John Weisgerberinventor
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Abstract
The present invention relates to enzyme variants having decreased immunogenicity relative to their corresponding wild-type enzymes. More particularly, the present invention relates to enzyme variants having a modified amino acid sequence of a wild-type amino acid sequence, wherein the modified amino acid sequence comprises a substitution of one or more amino acid positions with at least one D-amino acid. The invention further relates to mutant genes encoding such enzyme variants and cleaning and personal care compositions comprising such enzyme variants.
Claims17
An enzyme variant having a modified amino acid sequence of a wild-type amino acid sequence comprising a substitution by a substituting D-amino acid at one or more amino acid positions, wherein at least one amino acid of the enzyme variant is an L-amino acid.
Dependencies are inferred from the claim text.